Totir MA - Search Results

1

Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors.

Helfand MS, Taracila MA, Totir MA, Bonomo RA, Buynak JD, van den Akker F, Carey PR. Helfand MS, et al. Among authors: totir ma. Biochemistry. 2007 Jul 24;46(29):8689-99. doi: 10.1021/bi700581q. Epub 2007 Jun 27. Biochemistry. 2007. PMID: 17595114

2

Following the reactions of mechanism-based inhibitors with beta-lactamase by Raman crystallography.

Helfand MS, Totir MA, Carey MP, Hujer AM, Bonomo RA, Carey PR. Helfand MS, et al. Among authors: totir ma. Biochemistry. 2003 Nov 25;42(46):13386-92. doi: 10.1021/bi035716w. Biochemistry. 2003. PMID: 14621983

3

Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure.

Padayatti PS, Helfand MS, Totir MA, Carey MP, Hujer AM, Carey PR, Bonomo RA, van den Akker F. Padayatti PS, et al. Among authors: totir ma. Biochemistry. 2004 Feb 3;43(4):843-8. doi: 10.1021/bi035985m. Biochemistry. 2004. PMID: 14744126

4

High resolution crystal structures of the trans-enamine intermediates formed by sulbactam and clavulanic acid and E166A SHV-1 {beta}-lactamase.

Padayatti PS, Helfand MS, Totir MA, Carey MP, Carey PR, Bonomo RA, van den Akker F. Padayatti PS, et al. Among authors: totir ma. J Biol Chem. 2005 Oct 14;280(41):34900-7. doi: 10.1074/jbc.M505333200. Epub 2005 Jul 29. J Biol Chem. 2005. PMID: 16055923 Free article.

5

Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.

Totir MA, Padayatti PS, Helfand MS, Carey MP, Bonomo RA, Carey PR, van den Akker F. Totir MA, et al. Biochemistry. 2006 Oct 3;45(39):11895-904. doi: 10.1021/bi060990m. Biochemistry. 2006. PMID: 17002290 Free PMC article.

6

Rational design of a beta-lactamase inhibitor achieved via stabilization of the trans-enamine intermediate: 1.28 A crystal structure of wt SHV-1 complex with a penam sulfone.

Padayatti PS, Sheri A, Totir MA, Helfand MS, Carey MP, Anderson VE, Carey PR, Bethel CR, Bonomo RA, Buynak JD, van den Akker F. Padayatti PS, et al. Among authors: totir ma. J Am Chem Soc. 2006 Oct 11;128(40):13235-42. doi: 10.1021/ja063715w. J Am Chem Soc. 2006. PMID: 17017804 Free PMC article.

7

Sulbactam forms only minimal amounts of irreversible acrylate-enzyme with SHV-1 beta-lactamase.

Totir MA, Helfand MS, Carey MP, Sheri A, Buynak JD, Bonomo RA, Carey PR. Totir MA, et al. Biochemistry. 2007 Aug 7;46(31):8980-7. doi: 10.1021/bi7006146. Epub 2007 Jul 13. Biochemistry. 2007. PMID: 17630699 Free PMC article.

8

Why clinically used tazobactam and sulbactam are poor inhibitors of OXA-10 beta-lactamase: Raman crystallographic evidence.

Totir MA, Cha J, Ishiwata A, Wang B, Sheri A, Anderson VE, Buynak J, Mobashery S, Carey PR. Totir MA, et al. Biochemistry. 2008 Apr 1;47(13):4094-101. doi: 10.1021/bi702348w. Epub 2008 Mar 7. Biochemistry. 2008. PMID: 18324783

9

Different intermediate populations formed by tazobactam, sulbactam, and clavulanate reacting with SHV-1 beta-lactamases: Raman crystallographic evidence.

Kalp M, Totir MA, Buynak JD, Carey PR. Kalp M, et al. Among authors: totir ma. J Am Chem Soc. 2009 Feb 18;131(6):2338-47. doi: 10.1021/ja808311s. J Am Chem Soc. 2009. PMID: 19161282 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

9 results

Search Page

Filters