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Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule.
Murtazina R, Kovbasnjuk O, Zachos NC, Li X, Chen Y, Hubbard A, Hogema BM, Steplock D, Seidler U, Hoque KM, Tse CM, De Jonge HR, Weinman EJ, Donowitz M. Murtazina R, et al. Among authors: donowitz m. J Biol Chem. 2007 Aug 24;282(34):25141-51. doi: 10.1074/jbc.M701910200. Epub 2007 Jun 19. J Biol Chem. 2007. PMID: 17580307 Free article.
Molecular physiology of intestinal Na+/H+ exchange.
Zachos NC, Tse M, Donowitz M. Zachos NC, et al. Among authors: donowitz m. Annu Rev Physiol. 2005;67:411-43. doi: 10.1146/annurev.physiol.67.031103.153004. Annu Rev Physiol. 2005. PMID: 15709964 Review.
NHERF family and NHE3 regulation.
Donowitz M, Cha B, Zachos NC, Brett CL, Sharma A, Tse CM, Li X. Donowitz M, et al. J Physiol. 2005 Aug 15;567(Pt 1):3-11. doi: 10.1113/jphysiol.2005.090399. Epub 2005 May 19. J Physiol. 2005. PMID: 15905209 Free PMC article. Review.
Na+/H+ exchanger NHE3 activity and trafficking are lipid Raft-dependent.
Murtazina R, Kovbasnjuk O, Donowitz M, Li X. Murtazina R, et al. Among authors: donowitz m. J Biol Chem. 2006 Jun 30;281(26):17845-55. doi: 10.1074/jbc.M601740200. Epub 2006 Apr 27. J Biol Chem. 2006. PMID: 16648141 Free article.
J., Leung, G., Cheong, A., Louvard, D., and Donowitz, M. (2001) J. Physiol. (Lond.) 537, 537-552). Here, we examined the role of LR in NHE3 transport activity using a simpler system: opossum kidney (OK) cells (a renal proximal tubule epithelial cell line) containing …
J., Leung, G., Cheong, A., Louvard, D., and Donowitz, M. (2001) J. Physiol. (Lond.) 537, 537-552). Here, we examined the role …
Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.
Broere N, Hillesheim J, Tuo B, Jorna H, Houtsmuller AB, Shenolikar S, Weinman EJ, Donowitz M, Seidler U, de Jonge HR, Hogema BM. Broere N, et al. Among authors: donowitz m. J Biol Chem. 2007 Dec 28;282(52):37575-84. doi: 10.1074/jbc.M704878200. Epub 2007 Oct 18. J Biol Chem. 2007. PMID: 17947234 Free article.
Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.
Cunningham R, Esmaili A, Brown E, Biswas RS, Murtazina R, Donowitz M, Dijkman HB, van der Vlag J, Hogema BM, De Jonge HR, Shenolikar S, Wade JB, Weinman EJ. Cunningham R, et al. Among authors: donowitz m. Am J Physiol Renal Physiol. 2008 Apr;294(4):F1001-7. doi: 10.1152/ajprenal.00504.2007. Epub 2008 Feb 6. Am J Physiol Renal Physiol. 2008. PMID: 18256311 Free article.
NHE3 regulatory complexes.
Donowitz M, Mohan S, Zhu CX, Chen TE, Lin R, Cha B, Zachos NC, Murtazina R, Sarker R, Li X. Donowitz M, et al. J Exp Biol. 2009 Jun;212(Pt 11):1638-46. doi: 10.1242/jeb.028605. J Exp Biol. 2009. PMID: 19448074 Free PMC article. Review.
325 results