Campopiano DJ - Search Results

1

The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis.

Yard BA, Carter LG, Johnson KA, Overton IM, Dorward M, Liu H, McMahon SA, Oke M, Puech D, Barton GJ, Naismith JH, Campopiano DJ. Yard BA, et al. Among authors: campopiano dj. J Mol Biol. 2007 Jul 27;370(5):870-86. doi: 10.1016/j.jmb.2007.04.086. Epub 2007 May 10. J Mol Biol. 2007. PMID: 17559874

2

Coupled Natural Fusion Enzymes in a Novel Biocatalytic Cascade Convert Fatty Acids to Amines.

Richardson SM, Marchetti PM, Herrera MA, Campopiano DJ. Richardson SM, et al. Among authors: campopiano dj. ACS Catal. 2022 Oct 21;12(20):12701-12710. doi: 10.1021/acscatal.2c02954. Epub 2022 Oct 5. ACS Catal. 2022. PMID: 36313522 Free PMC article.

3

The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme.

Alexeev D, Alexeeva M, Baxter RL, Campopiano DJ, Webster SP, Sawyer L. Alexeev D, et al. Among authors: campopiano dj. J Mol Biol. 1998 Nov 27;284(2):401-19. doi: 10.1006/jmbi.1998.2086. J Mol Biol. 1998. PMID: 9813126

4

The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics.

Raman MCC, Johnson KA, Yard BA, Lowther J, Carter LG, Naismith JH, Campopiano DJ. Raman MCC, et al. Among authors: campopiano dj. J Biol Chem. 2009 Jun 19;284(25):17328-17339. doi: 10.1074/jbc.M109.008680. Epub 2009 Apr 17. J Biol Chem. 2009. PMID: 19376777 Free PMC article.

5

Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.

Tron CM, McNae IW, Nutley M, Clarke DJ, Cooper A, Walkinshaw MD, Baxter RL, Campopiano DJ. Tron CM, et al. Among authors: campopiano dj. J Mol Biol. 2009 Mar 20;387(1):129-46. doi: 10.1016/j.jmb.2008.12.086. J Mol Biol. 2009. PMID: 19385043 Free article.

6

Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.

Lowther J, Yard BA, Johnson KA, Carter LG, Bhat VT, Raman MC, Clarke DJ, Ramakers B, McMahon SA, Naismith JH, Campopiano DJ. Lowther J, et al. Among authors: campopiano dj. Mol Biosyst. 2010 Sep;6(9):1682-93. doi: 10.1039/c003743e. Epub 2010 May 5. Mol Biosyst. 2010. PMID: 20445930 Free PMC article.

7

The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein.

Raman MC, Johnson KA, Clarke DJ, Naismith JH, Campopiano DJ. Raman MC, et al. Among authors: campopiano dj. Biopolymers. 2010 Sep;93(9):811-22. doi: 10.1002/bip.21482. Biopolymers. 2010. PMID: 20578000 Free article.

8

Role of a conserved arginine residue during catalysis in serine palmitoyltransferase.

Lowther J, Charmier G, Raman MC, Ikushiro H, Hayashi H, Campopiano DJ. Lowther J, et al. Among authors: campopiano dj. FEBS Lett. 2011 Jun 23;585(12):1729-34. doi: 10.1016/j.febslet.2011.04.013. Epub 2011 Apr 18. FEBS Lett. 2011. PMID: 21514297 Free article.

9

Structural, mechanistic and regulatory studies of serine palmitoyltransferase.

Lowther J, Naismith JH, Dunn TM, Campopiano DJ. Lowther J, et al. Among authors: campopiano dj. Biochem Soc Trans. 2012 Jun 1;40(3):547-54. doi: 10.1042/BST20110769. Biochem Soc Trans. 2012. PMID: 22616865 Free article. Review.

10

Reconstitution of the pyridoxal 5'-phosphate (PLP) dependent enzyme serine palmitoyltransferase (SPT) with pyridoxal reveals a crucial role for the phosphate during catalysis.

Beattie AE, Clarke DJ, Wadsworth JM, Lowther J, Sin HL, Campopiano DJ. Beattie AE, et al. Among authors: campopiano dj. Chem Commun (Camb). 2013 Aug 14;49(63):7058-60. doi: 10.1039/c3cc43001d. Chem Commun (Camb). 2013. PMID: 23814788 Free article.

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