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Quantitative structure--activity relationship analysis and molecular dynamics simulation to functionally validate nonsynonymous polymorphisms of human ABC transporter ABCB1 (P-glycoprotein/MDR1).
Sakurai A, Onishi Y, Hirano H, Seigneuret M, Obanayama K, Kim G, Liew EL, Sakaeda T, Yoshiura K, Niikawa N, Sakurai M, Ishikawa T. Sakurai A, et al. Among authors: sakurai m. Biochemistry. 2007 Jul 3;46(26):7678-93. doi: 10.1021/bi700330b. Epub 2007 Jun 9. Biochemistry. 2007. PMID: 17559192
Emerging new technologies in Pharmacogenomics: rapid SNP detection, molecular dynamic simulation, and QSAR analysis methods to validate clinically important genetic variants of human ABC Transporter ABCB1 (P-gp/MDR1).
Ishikawa T, Sakurai A, Hirano H, Lezhava A, Sakurai M, Hayashizaki Y. Ishikawa T, et al. Among authors: sakurai a, sakurai m. Pharmacol Ther. 2010 Apr;126(1):69-81. doi: 10.1016/j.pharmthera.2010.01.005. Epub 2010 Feb 4. Pharmacol Ther. 2010. PMID: 20138191 Review.
2,149 results