Zhang S - Search Results

1

An affinity-based fluorescence polarization assay for protein tyrosine phosphatases.

Zhang S, Chen L, Kumar S, Wu L, Lawrence DS, Zhang ZY. Zhang S, et al. Among authors: zhang zy. Methods. 2007 Jul;42(3):261-7. doi: 10.1016/j.ymeth.2007.02.008. Methods. 2007. PMID: 17532513 Free PMC article.

2

PTP1B as a drug target: recent developments in PTP1B inhibitor discovery.

Zhang S, Zhang ZY. Zhang S, et al. Among authors: zhang zy. Drug Discov Today. 2007 May;12(9-10):373-81. doi: 10.1016/j.drudis.2007.03.011. Epub 2007 Apr 6. Drug Discov Today. 2007. PMID: 17467573 Review.

3

Small molecule tools for functional interrogation of protein tyrosine phosphatases.

He R, Zeng LF, He Y, Zhang S, Zhang ZY. He R, et al. Among authors: zhang s, zhang zy. FEBS J. 2013 Jan;280(2):731-50. doi: 10.1111/j.1742-4658.2012.08718.x. Epub 2012 Aug 16. FEBS J. 2013. PMID: 22816879 Free PMC article. Review.

4

A combinatorial strategy for the acquisition of potent and specific protein tyrosine phosphatase inhibitors.

Zhang S, Chen L, Lawrence DS, Zhang ZY. Zhang S, et al. Among authors: zhang zy. Methods Mol Biol. 2012;928:53-65. doi: 10.1007/978-1-62703-008-3_5. Methods Mol Biol. 2012. PMID: 22956133 Free PMC article.

5

SHP2 phosphatase as a novel therapeutic target for melanoma treatment.

Zhang RY, Yu ZH, Zeng L, Zhang S, Bai Y, Miao J, Chen L, Xie J, Zhang ZY. Zhang RY, et al. Among authors: zhang s, zhang zy. Oncotarget. 2016 Nov 8;7(45):73817-73829. doi: 10.18632/oncotarget.12074. Oncotarget. 2016. PMID: 27650545 Free PMC article.

6

Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2.

Zhang RY, Yu ZH, Chen L, Walls CD, Zhang S, Wu L, Zhang ZY. Zhang RY, et al. Among authors: zhang s, zhang zy. J Biol Chem. 2020 May 1;295(18):6187-6201. doi: 10.1074/jbc.RA119.010274. Epub 2020 Mar 18. J Biol Chem. 2020. PMID: 32188694 Free PMC article.

7

Acquisition of a potent and selective TC-PTP inhibitor via a stepwise fluorophore-tagged combinatorial synthesis and screening strategy.

Zhang S, Chen L, Luo Y, Gunawan A, Lawrence DS, Zhang ZY. Zhang S, et al. Among authors: zhang zy. J Am Chem Soc. 2009 Sep 16;131(36):13072-9. doi: 10.1021/ja903733z. J Am Chem Soc. 2009. PMID: 19737019 Free PMC article.

8

Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.

Chen L, Zhou B, Zhang S, Wu L, Wang Y, Franzblau SG, Zhang ZY. Chen L, et al. Among authors: zhang s, zhang zy. ACS Med Chem Lett. 2010 Oct 14;1(7):355-359. doi: 10.1021/ml1001135. ACS Med Chem Lett. 2010. PMID: 21116447 Free PMC article.

9

Substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate.

Yu X, Chen M, Zhang S, Yu ZH, Sun JP, Wang L, Liu S, Imasaki T, Takagi Y, Zhang ZY. Yu X, et al. Among authors: zhang s, zhang zy. J Biol Chem. 2011 Sep 2;286(35):30526-30534. doi: 10.1074/jbc.M111.254722. Epub 2011 Jun 30. J Biol Chem. 2011. PMID: 21719704 Free PMC article.

10

A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.

Zhang S, Liu S, Tao R, Wei D, Chen L, Shen W, Yu ZH, Wang L, Jones DR, Dong XC, Zhang ZY. Zhang S, et al. Among authors: zhang zy. J Am Chem Soc. 2012 Oct 31;134(43):18116-24. doi: 10.1021/ja308212y. Epub 2012 Oct 17. J Am Chem Soc. 2012. PMID: 23075115 Free PMC article.

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