Wu L - Search Results

1

An affinity-based fluorescence polarization assay for protein tyrosine phosphatases.

Zhang S, Chen L, Kumar S, Wu L, Lawrence DS, Zhang ZY. Zhang S, et al. Among authors: wu l. Methods. 2007 Jul;42(3):261-7. doi: 10.1016/j.ymeth.2007.02.008. Methods. 2007. PMID: 17532513 Free PMC article.

2

Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.

Liu S, Zhou B, Yang H, He Y, Jiang ZX, Kumar S, Wu L, Zhang ZY. Liu S, et al. Among authors: wu l. J Am Chem Soc. 2008 Jul 2;130(26):8251-60. doi: 10.1021/ja711125p. Epub 2008 Jun 4. J Am Chem Soc. 2008. PMID: 18528979 Free PMC article.

3

Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.

Yu ZH, Chen L, Wu L, Liu S, Wang L, Zhang ZY. Yu ZH, et al. Among authors: wu l. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4238-42. doi: 10.1016/j.bmcl.2011.05.078. Epub 2011 May 30. Bioorg Med Chem Lett. 2011. PMID: 21669525 Free PMC article.

4

Suramin derivatives as inhibitors and activators of protein-tyrosine phosphatases.

McCain DF, Wu L, Nickel P, Kassack MU, Kreimeyer A, Gagliardi A, Collins DC, Zhang ZY. McCain DF, et al. Among authors: wu l. J Biol Chem. 2004 Apr 9;279(15):14713-25. doi: 10.1074/jbc.M312488200. Epub 2004 Jan 20. J Biol Chem. 2004. PMID: 14734566 Free article.

5

Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors.

Liu S, Zeng LF, Wu L, Yu X, Xue T, Gunawan AM, Long YQ, Zhang ZY. Liu S, et al. Among authors: wu l. J Am Chem Soc. 2008 Dec 17;130(50):17075-84. doi: 10.1021/ja8068177. J Am Chem Soc. 2008. PMID: 19012396 Free PMC article.

6

Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).

Zhang X, He Y, Liu S, Yu Z, Jiang ZX, Yang Z, Dong Y, Nabinger SC, Wu L, Gunawan AM, Wang L, Chan RJ, Zhang ZY. Zhang X, et al. Among authors: wu l. J Med Chem. 2010 Mar 25;53(6):2482-93. doi: 10.1021/jm901645u. J Med Chem. 2010. PMID: 20170098 Free PMC article.

7

Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor.

He R, Yu Z, He Y, Zeng LF, Xu J, Wu L, Gunawan AM, Wang L, Jiang ZX, Zhang ZY. He R, et al. Among authors: wu l. ChemMedChem. 2010 Dec 3;5(12):2051-6. doi: 10.1002/cmdc.201000348. ChemMedChem. 2010. PMID: 20957718 Free PMC article.

8

Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.

Chen L, Zhou B, Zhang S, Wu L, Wang Y, Franzblau SG, Zhang ZY. Chen L, et al. Among authors: wu l. ACS Med Chem Lett. 2010 Oct 14;1(7):355-359. doi: 10.1021/ml1001135. ACS Med Chem Lett. 2010. PMID: 21116447 Free PMC article.

9

Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.

He Y, Xu J, Yu ZH, Gunawan AM, Wu L, Wang L, Zhang ZY. He Y, et al. Among authors: wu l. J Med Chem. 2013 Feb 14;56(3):832-42. doi: 10.1021/jm301781p. Epub 2013 Jan 25. J Med Chem. 2013. PMID: 23305444 Free PMC article.

10

Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis.

He R, Zeng LF, He Y, Wu L, Gunawan AM, Zhang ZY. He R, et al. Among authors: wu l. Chem Commun (Camb). 2013 Mar 11;49(20):2064-6. doi: 10.1039/c3cc38961h. Chem Commun (Camb). 2013. PMID: 23380872 Free PMC article.

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