Raes AL - Search Results

1

A single hERG mutation underlying a spectrum of acquired and congenital long QT syndrome phenotypes.

Saenen JB, Paulussen AD, Jongbloed RJ, Marcelis CL, Gilissen RA, Aerssens J, Snyders DJ, Raes AL. Saenen JB, et al. Among authors: raes al. J Mol Cell Cardiol. 2007 Jul;43(1):63-72. doi: 10.1016/j.yjmcc.2007.04.012. Epub 2007 May 4. J Mol Cell Cardiol. 2007. PMID: 17531263

2

Functional effects of a KCNQ1 mutation associated with the long QT syndrome.

Boulet IR, Raes AL, Ottschytsch N, Snyders DJ. Boulet IR, et al. Among authors: raes al. Cardiovasc Res. 2006 Jun 1;70(3):466-74. doi: 10.1016/j.cardiores.2006.02.006. Epub 2006 Feb 28. Cardiovasc Res. 2006. PMID: 16564513

3

A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency.

Paulussen A, Raes A, Matthijs G, Snyders DJ, Cohen N, Aerssens J. Paulussen A, et al. J Biol Chem. 2002 Dec 13;277(50):48610-6. doi: 10.1074/jbc.M206569200. Epub 2002 Sep 26. J Biol Chem. 2002. PMID: 12354768 Free article.

4

Modulation of HERG gating by a charge cluster in the N-terminal proximal domain.

Saenen JB, Labro AJ, Raes A, Snyders DJ. Saenen JB, et al. Biophys J. 2006 Dec 15;91(12):4381-91. doi: 10.1529/biophysj.106.087247. Epub 2006 Sep 22. Biophys J. 2006. PMID: 16997865 Free PMC article.

5

Differential modulation of Kv4 kinetics by KCHIP1 splice variants.

Van Hoorick D, Raes A, Keysers W, Mayeur E, Snyders DJ. Van Hoorick D, et al. Mol Cell Neurosci. 2003 Oct;24(2):357-66. doi: 10.1016/s1044-7431(03)00174-x. Mol Cell Neurosci. 2003. PMID: 14572458

6

HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.

Paulussen AD, Raes A, Jongbloed RJ, Gilissen RA, Wilde AA, Snyders DJ, Smeets HJ, Aerssens J. Paulussen AD, et al. Cardiovasc Res. 2005 Aug 15;67(3):467-75. doi: 10.1016/j.cardiores.2005.05.017. Cardiovasc Res. 2005. PMID: 15958262

7

Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.

Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ. Ottschytsch N, et al. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7986-91. doi: 10.1073/pnas.122617999. Proc Natl Acad Sci U S A. 2002. PMID: 12060745 Free PMC article.

8

The aromatic cluster in KCHIP1b affects Kv4 inactivation gating.

Van Hoorick D, Raes A, Snyders DJ. Van Hoorick D, et al. J Physiol. 2007 Sep 15;583(Pt 3):959-69. doi: 10.1113/jphysiol.2007.139550. Epub 2007 Jul 19. J Physiol. 2007. PMID: 17640927 Free PMC article.

9

Coupling of voltage sensing to channel opening reflects intrasubunit interactions in kv channels.

Labro AJ, Raes AL, Snyders DJ. Labro AJ, et al. Among authors: raes al. J Gen Physiol. 2005 Jan;125(1):71-80. doi: 10.1085/jgp.200409194. J Gen Physiol. 2005. PMID: 15623896 Free PMC article.

10

Domain analysis of Kv6.3, an electrically silent channel.

Ottschytsch N, Raes AL, Timmermans JP, Snyders DJ. Ottschytsch N, et al. Among authors: raes al. J Physiol. 2005 Nov 1;568(Pt 3):737-47. doi: 10.1113/jphysiol.2005.090142. Epub 2005 Aug 11. J Physiol. 2005. PMID: 16096342 Free PMC article.

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