Cole PA - Search Results

1

Mechanistic analysis of a suicide inactivator of histone demethylase LSD1.

Szewczuk LM, Culhane JC, Yang M, Majumdar A, Yu H, Cole PA. Szewczuk LM, et al. Among authors: cole pa. Biochemistry. 2007 Jun 12;46(23):6892-902. doi: 10.1021/bi700414b. Epub 2007 May 19. Biochemistry. 2007. PMID: 17511474 Free PMC article.

2

Molecular determinants for Csk-catalyzed tyrosine phosphorylation of the Src tail.

Wang D, Huang XY, Cole PA. Wang D, et al. Among authors: cole pa. Biochemistry. 2001 Feb 20;40(7):2004-10. doi: 10.1021/bi002342n. Biochemistry. 2001. PMID: 11329267

3

Chemical dissection of the effects of tyrosine phosphorylation of SHP-2.

Lu W, Shen K, Cole PA. Lu W, et al. Among authors: cole pa. Biochemistry. 2003 May 13;42(18):5461-8. doi: 10.1021/bi0340144. Biochemistry. 2003. PMID: 12731888

4

Fluorescence analysis of a dynamic loop in the PCAF/GCN5 histone acetyltransferase.

Zheng Y, Mamdani F, Toptygin D, Brand L, Stivers JT, Cole PA. Zheng Y, et al. Among authors: cole pa. Biochemistry. 2005 Aug 9;44(31):10501-9. doi: 10.1021/bi050776i. Biochemistry. 2005. PMID: 16060659

5

A mechanism-based inactivator for histone demethylase LSD1.

Culhane JC, Szewczuk LM, Liu X, Da G, Marmorstein R, Cole PA. Culhane JC, et al. Among authors: cole pa. J Am Chem Soc. 2006 Apr 12;128(14):4536-7. doi: 10.1021/ja0602748. J Am Chem Soc. 2006. PMID: 16594666

6

Structural basis of histone demethylation by LSD1 revealed by suicide inactivation.

Yang M, Culhane JC, Szewczuk LM, Gocke CB, Brautigam CA, Tomchick DR, Machius M, Cole PA, Yu H. Yang M, et al. Among authors: cole pa. Nat Struct Mol Biol. 2007 Jun;14(6):535-9. doi: 10.1038/nsmb1255. Epub 2007 May 27. Nat Struct Mol Biol. 2007. PMID: 17529991

7

Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine.

Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Yang M, et al. Among authors: cole pa. Biochemistry. 2007 Jul 10;46(27):8058-65. doi: 10.1021/bi700664y. Epub 2007 Jun 15. Biochemistry. 2007. PMID: 17569509

8

Multiple roles for acetylation in the interaction of p300 HAT with ATF-2.

Karanam B, Wang L, Wang D, Liu X, Marmorstein R, Cotter R, Cole PA. Karanam B, et al. Among authors: cole pa. Biochemistry. 2007 Jul 17;46(28):8207-16. doi: 10.1021/bi7000054. Epub 2007 Jun 23. Biochemistry. 2007. PMID: 17590016 Free PMC article.

9

LSD1 and the chemistry of histone demethylation.

Culhane JC, Cole PA. Culhane JC, et al. Among authors: cole pa. Curr Opin Chem Biol. 2007 Oct;11(5):561-8. doi: 10.1016/j.cbpa.2007.07.014. Epub 2007 Sep 11. Curr Opin Chem Biol. 2007. PMID: 17851108 Free PMC article. Review.

10

De novo discovery of serotonin N-acetyltransferase inhibitors.

Szewczuk LM, Saldanha SA, Ganguly S, Bowers EM, Javoroncov M, Karanam B, Culhane JC, Holbert MA, Klein DC, Abagyan R, Cole PA. Szewczuk LM, et al. Among authors: cole pa. J Med Chem. 2007 Nov 1;50(22):5330-8. doi: 10.1021/jm0706463. Epub 2007 Oct 9. J Med Chem. 2007. PMID: 17924613 Free PMC article.

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