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Heterologous mRNA-protein vaccination with Tc24 induces a robust cellular immune response against Trypanosoma cruzi, characterized by an increased level of polyfunctional CD8+ T-cells.
Poveda C, Leão AC, Mancino C, Taraballi F, Chen YL, Adhikari R, Villar MJ, Kundu R, Nguyen DM, Versteeg L, Strych U, Hotez PJ, Bottazzi ME, Pollet J, Jones KM. Poveda C, et al. Among authors: strych u. Curr Res Immunol. 2023 Jul 20;4:100066. doi: 10.1016/j.crimmu.2023.100066. eCollection 2023. Curr Res Immunol. 2023. PMID: 37534309 Free PMC article.
The potential epidemiologic, clinical, and economic value of a universal coronavirus vaccine: a modelling study.
Bartsch SM, O'Shea KJ, John DC, Strych U, Bottazzi ME, Martinez MF, Ciciriello A, Chin KL, Weatherwax C, Velmurugan K, Heneghan J, Scannell SA, Hotez PJ, Lee BY. Bartsch SM, et al. Among authors: strych u. EClinicalMedicine. 2024 Jan 11;68:102369. doi: 10.1016/j.eclinm.2023.102369. eCollection 2024 Feb. EClinicalMedicine. 2024. PMID: 38545093 Free PMC article.
The zebrafish as a potential model for vaccine and adjuvant development.
Hotez PJ, Bottazzi ME, Islam NY, Lee J, Pollet J, Poveda C, Strych U, Thimmiraju SR, Uzcategui NL, Versteeg L, Gorelick D. Hotez PJ, et al. Among authors: strych u. Expert Rev Vaccines. 2024 Jan-Dec;23(1):535-545. doi: 10.1080/14760584.2024.2345685. Epub 2024 May 9. Expert Rev Vaccines. 2024. PMID: 38664959 Free article. Review.
A Data-Driven Approach to Construct a Molecular Map of Trypanosoma cruzi to Identify Drugs and Vaccine Targets.
Nath SK, Pankajakshan P, Sharma T, Kumari P, Shinde S, Garg N, Mathur K, Arambam N, Harjani D, Raj M, Kwatra G, Venkatesh S, Choudhoury A, Bano S, Tayal P, Sharan M, Arora R, Strych U, Hotez PJ, Bottazzi ME, Rawal K. Nath SK, et al. Among authors: strych u. Vaccines (Basel). 2023 Jan 26;11(2):267. doi: 10.3390/vaccines11020267. Vaccines (Basel). 2023. PMID: 36851145 Free PMC article.
From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access.
Hotez PJ, Adhikari R, Chen WH, Chen YL, Gillespie P, Islam NY, Keegan B, Tyagi Kundu R, Lee J, Liu Z, Kimata JT, Oezguen N, Pollet J, Poveda C, Razavi K, Ronca SE, Strych U, Thimmiraju SR, Versteeg L, Villar-Mondragon MJ, Wei J, Zhan B, Bottazzi ME. Hotez PJ, et al. Among authors: strych u. Expert Rev Vaccines. 2023 Jan-Dec;22(1):495-500. doi: 10.1080/14760584.2023.2217917. Expert Rev Vaccines. 2023. PMID: 37252854 Free article.
Serratia marcescens and its extracellular nuclease.
Benedik MJ, Strych U. Benedik MJ, et al. Among authors: strych u. FEMS Microbiol Lett. 1998 Aug 1;165(1):1-13. doi: 10.1111/j.1574-6968.1998.tb13120.x. FEMS Microbiol Lett. 1998. PMID: 9711834 Review.
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