Scozzafava A - Search Results

1

Imaging the hypoxia surrogate marker CA IX requires expression and catalytic activity for binding fluorescent sulfonamide inhibitors.

Dubois L, Douma K, Supuran CT, Chiu RK, van Zandvoort MA, Pastoreková S, Scozzafava A, Wouters BG, Lambin P. Dubois L, et al. Among authors: scozzafava a. Radiother Oncol. 2007 Jun;83(3):367-73. doi: 10.1016/j.radonc.2007.04.018. Epub 2007 May 14. Radiother Oncol. 2007. PMID: 17502120

2

Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model.

Dubois L, Lieuwes NG, Maresca A, Thiry A, Supuran CT, Scozzafava A, Wouters BG, Lambin P. Dubois L, et al. Among authors: scozzafava a. Radiother Oncol. 2009 Sep;92(3):423-8. doi: 10.1016/j.radonc.2009.06.019. Epub 2009 Jul 16. Radiother Oncol. 2009. PMID: 19616332

3

Specific inhibition of carbonic anhydrase IX activity enhances the in vivo therapeutic effect of tumor irradiation.

Dubois L, Peeters S, Lieuwes NG, Geusens N, Thiry A, Wigfield S, Carta F, McIntyre A, Scozzafava A, Dogné JM, Supuran CT, Harris AL, Masereel B, Lambin P. Dubois L, et al. Among authors: scozzafava a. Radiother Oncol. 2011 Jun;99(3):424-31. doi: 10.1016/j.radonc.2011.05.045. Epub 2011 Jun 14. Radiother Oncol. 2011. PMID: 21676479 Free article.

4

Carbonic anhydrase inhibitors.

Supuran CT, Scozzafava A, Casini A. Supuran CT, et al. Among authors: scozzafava a. Med Res Rev. 2003 Mar;23(2):146-89. doi: 10.1002/med.10025. Med Res Rev. 2003. PMID: 12500287 Review.

5

Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX.

Pastorekova S, Casini A, Scozzafava A, Vullo D, Pastorek J, Supuran CT. Pastorekova S, et al. Among authors: scozzafava a. Bioorg Med Chem Lett. 2004 Feb 23;14(4):869-73. doi: 10.1016/j.bmcl.2003.12.029. Bioorg Med Chem Lett. 2004. PMID: 15012984

6

Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with fluorine-containing sulfonamides. The first subnanomolar CA IX inhibitor discovered.

Vullo D, Scozzafava A, Pastorekova S, Pastorek J, Supuran CT. Vullo D, et al. Among authors: scozzafava a. Bioorg Med Chem Lett. 2004 May 3;14(9):2351-6. doi: 10.1016/j.bmcl.2004.01.095. Bioorg Med Chem Lett. 2004. PMID: 15081039

7

Redox state and carbonic anhydrase isozyme IX expression in human renal cell carcinoma: biochemical and morphological investigations.

Tripodi SA, Del Vecchio MT, Supuran CT, Scozzafava A, Gabrielli MG, Pastorekova S, Rossie R, Fasolis G, Puccetti L. Tripodi SA, et al. Among authors: scozzafava a. J Enzyme Inhib Med Chem. 2004 Jun;19(3):287-91. doi: 10.1080/14756360410001689531. J Enzyme Inhib Med Chem. 2004. PMID: 15500003 Free article.

8

Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.

Cecchi A, Hulikova A, Pastorek J, Pastoreková S, Scozzafava A, Winum JY, Montero JL, Supuran CT. Cecchi A, et al. Among authors: scozzafava a. J Med Chem. 2005 Jul 28;48(15):4834-41. doi: 10.1021/jm0501073. J Med Chem. 2005. PMID: 16033263

9

Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with polyfluorinated aromatic/heterocyclic sulfonamides.

Pastorekova S, Vullo D, Casini A, Scozzafava A, Pastorek J, Nishimori I, Supuran CT. Pastorekova S, et al. Among authors: scozzafava a. J Enzyme Inhib Med Chem. 2005 Jun;20(3):211-7. doi: 10.1080/14756360400028101. J Enzyme Inhib Med Chem. 2005. PMID: 16119190 Free article.

10

Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.

Said HM, Hagemann C, Carta F, Katzer A, Polat B, Staab A, Scozzafava A, Anacker J, Vince GH, Flentje M, Supuran CT. Said HM, et al. Among authors: scozzafava a. Bioorg Med Chem. 2013 Jul 1;21(13):3949-57. doi: 10.1016/j.bmc.2013.03.068. Epub 2013 Apr 12. Bioorg Med Chem. 2013. PMID: 23706268

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