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Contribution of itraconazole metabolites to inhibition of CYP3A4 in vivo.
Templeton IE, Thummel KE, Kharasch ED, Kunze KL, Hoffer C, Nelson WL, Isoherranen N. Templeton IE, et al. Among authors: nelson wl. Clin Pharmacol Ther. 2008 Jan;83(1):77-85. doi: 10.1038/sj.clpt.6100230. Epub 2007 May 9. Clin Pharmacol Ther. 2008. PMID: 17495874 Free PMC article. Clinical Trial.
Role of itraconazole metabolites in CYP3A4 inhibition.
Isoherranen N, Kunze KL, Allen KE, Nelson WL, Thummel KE. Isoherranen N, et al. Among authors: nelson wl. Drug Metab Dispos. 2004 Oct;32(10):1121-31. doi: 10.1124/dmd.104.000315. Epub 2004 Jul 8. Drug Metab Dispos. 2004. PMID: 15242978
Sequential metabolism of secondary alkyl amines to metabolic-intermediate complexes: opposing roles for the secondary hydroxylamine and primary amine metabolites of desipramine, (s)-fluoxetine, and N-desmethyldiltiazem.
Hanson KL, VandenBrink BM, Babu KN, Allen KE, Nelson WL, Kunze KL. Hanson KL, et al. Among authors: nelson wl. Drug Metab Dispos. 2010 Jun;38(6):963-72. doi: 10.1124/dmd.110.032391. Epub 2010 Mar 3. Drug Metab Dispos. 2010. PMID: 20200233 Free PMC article.
178 results