Yancopoulos GD - Search Results

1

The Delta paradox: DLL4 blockade leads to more tumour vessels but less tumour growth.

Thurston G, Noguera-Troise I, Yancopoulos GD. Thurston G, et al. Among authors: yancopoulos gd. Nat Rev Cancer. 2007 May;7(5):327-31. doi: 10.1038/nrc2130. Nat Rev Cancer. 2007. PMID: 17457300 Review.

2

Inhibitors of growth factor receptors, signaling pathways and angiogenesis as therapeutic molecular agents.

Holash J, Thurston G, Rudge JS, Yancopoulos GD, Adjei AA, Bergers G, Pytowski B, Pegram M, Gordon MS. Holash J, et al. Among authors: yancopoulos gd. Cancer Metastasis Rev. 2006 Jun;25(2):243-52. doi: 10.1007/s10555-006-8504-6. Cancer Metastasis Rev. 2006. PMID: 16770536 Review. No abstract available.

3

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis.

Noguera-Troise I, Daly C, Papadopoulos NJ, Coetzee S, Boland P, Gale NW, Lin HC, Yancopoulos GD, Thurston G. Noguera-Troise I, et al. Among authors: yancopoulos gd. Nature. 2006 Dec 21;444(7122):1032-7. doi: 10.1038/nature05355. Nature. 2006. PMID: 17183313

4

Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis.

Noguera-Troise I, Daly C, Papadopoulos NJ, Coetzee S, Boland P, Gale NW, Lin HC, Yancopoulos GD, Thurston G. Noguera-Troise I, et al. Among authors: yancopoulos gd. Novartis Found Symp. 2007;283:106-20; discussion 121-5, 238-41. Novartis Found Symp. 2007. PMID: 18300417

5

Resistance to Anti-VEGF Therapy Mediated by Autocrine IL6/STAT3 Signaling and Overcome by IL6 Blockade.

Eichten A, Su J, Adler AP, Zhang L, Ioffe E, Parveen AA, Yancopoulos GD, Rudge J, Lowy I, Lin HC, MacDonald D, Daly C, Duan X, Thurston G. Eichten A, et al. Among authors: yancopoulos gd. Cancer Res. 2016 Apr 15;76(8):2327-39. doi: 10.1158/0008-5472.CAN-15-1443. Epub 2016 Feb 26. Cancer Res. 2016. PMID: 26921327

6

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting.

Lobov IB, Renard RA, Papadopoulos N, Gale NW, Thurston G, Yancopoulos GD, Wiegand SJ. Lobov IB, et al. Among authors: yancopoulos gd. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3219-24. doi: 10.1073/pnas.0611206104. Epub 2007 Feb 12. Proc Natl Acad Sci U S A. 2007. PMID: 17296940 Free PMC article.

7

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

Gale NW, Thurston G, Hackett SF, Renard R, Wang Q, McClain J, Martin C, Witte C, Witte MH, Jackson D, Suri C, Campochiaro PA, Wiegand SJ, Yancopoulos GD. Gale NW, et al. Among authors: yancopoulos gd. Dev Cell. 2002 Sep;3(3):411-23. doi: 10.1016/s1534-5807(02)00217-4. Dev Cell. 2002. PMID: 12361603 Free article.

8

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.

Gale NW, Dominguez MG, Noguera I, Pan L, Hughes V, Valenzuela DM, Murphy AJ, Adams NC, Lin HC, Holash J, Thurston G, Yancopoulos GD. Gale NW, et al. Among authors: yancopoulos gd. Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15949-54. doi: 10.1073/pnas.0407290101. Epub 2004 Nov 1. Proc Natl Acad Sci U S A. 2004. PMID: 15520367 Free PMC article.

9

The anti-inflammatory actions of angiopoietin-1.

Thurston G, Rudge JS, Ioffe E, Papadopoulos N, Daly C, Vuthoori S, Daly T, Wiegand SJ, Yancopoulos GD. Thurston G, et al. Among authors: yancopoulos gd. EXS. 2005;(94):233-45. doi: 10.1007/3-7643-7311-3_16. EXS. 2005. PMID: 15617482 Review. No abstract available.

10

Angiopoietin 1 causes vessel enlargement, without angiogenic sprouting, during a critical developmental period.

Thurston G, Wang Q, Baffert F, Rudge J, Papadopoulos N, Jean-Guillaume D, Wiegand S, Yancopoulos GD, McDonald DM. Thurston G, et al. Among authors: yancopoulos gd. Development. 2005 Jul;132(14):3317-26. doi: 10.1242/dev.01888. Epub 2005 Jun 15. Development. 2005. PMID: 15958513

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