Chiara JL - Search Results

1

Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors.

Gibson RP, Gloster TM, Roberts S, Warren RA, Storch de Gracia I, García A, Chiara JL, Davies GJ. Gibson RP, et al. Among authors: chiara jl. Angew Chem Int Ed Engl. 2007;46(22):4115-9. doi: 10.1002/anie.200604825. Angew Chem Int Ed Engl. 2007. PMID: 17455176 No abstract available.

2

Synthesis, inhibition properties, and theoretical study of the new nanomolar trehalase inhibitor 1-thiatrehazolin: towards a structural understanding of trehazolin inhibition.

Chiara JL, Storch de Gracia I, García A, Bastida A, Bobo S, Martín-Ortega MD. Chiara JL, et al. Chembiochem. 2005 Jan;6(1):186-91. doi: 10.1002/cbic.200400231. Chembiochem. 2005. PMID: 15532066

3

Synthesis of the aminocyclopentitol moieties of the hopanoids of Zymomonas mobilis and 'Anacystis montana'.

Chiara JL, Storch de Gracia I, Bastida A. Chiara JL, et al. Chem Commun (Camb). 2003 Aug 7;(15):1874-5. doi: 10.1039/b304576e. Chem Commun (Camb). 2003. PMID: 12932010

4

Ketone-imide versus ketone-oxime reductive cross-coupling promoted by samarium diiodide: new mechanistic insight gained from a failed aminocyclopentitol synthesis.

Chiara JL, García A, Cristóbal-Lumbroso G. Chiara JL, et al. J Org Chem. 2005 May 13;70(10):4142-51. doi: 10.1021/jo050185y. J Org Chem. 2005. PMID: 15876107 Free article.

5

A Highly Efficient Pinacol Coupling Approach to Trehazolamine Starting from D-Glucose.

Storch De Gracia I, Dietrich H, Bobo S, Chiara JL. Storch De Gracia I, et al. Among authors: chiara jl. J Org Chem. 1998 Aug 21;63(17):5883-5889. doi: 10.1021/jo980831b. J Org Chem. 1998. PMID: 11672191

6

1-silyl-2,6-diketones: versatile intermediates for the divergent synthesis of five- and six-membered carbocycles under radical and anionic conditions.

Chiara JL, García A, Sesmilo E, Vacas T. Chiara JL, et al. Org Lett. 2006 Aug 31;8(18):3935-8. doi: 10.1021/ol0613517. Org Lett. 2006. PMID: 16928042

7

Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance.

Bastida A, Hidalgo A, Chiara JL, Torrado M, Corzana F, Pérez-Cañadillas JM, Groves P, Garcia-Junceda E, Gonzalez C, Jimenez-Barbero J, Asensio JL. Bastida A, et al. Among authors: chiara jl. J Am Chem Soc. 2006 Jan 11;128(1):100-16. doi: 10.1021/ja0543144. J Am Chem Soc. 2006. PMID: 16390137 Free article.

8

A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.

Asensio JL, Hidalgo A, Bastida A, Torrado M, Corzana F, Chiara JL, García-Junceda E, Cañada J, Jiménez-Barbero J. Asensio JL, et al. Among authors: chiara jl. J Am Chem Soc. 2005 Jun 15;127(23):8278-9. doi: 10.1021/ja051722z. J Am Chem Soc. 2005. PMID: 15941249 Free article.

9

Experimental evidence for the existence of non-exo-anomeric conformations in branched oligosaccharides: the neomycin-B case.

Asensio JL, Hidalgo A, Cuesta I, Gonzalez C, Cañada J, Vicent C, Chiara JL, Cuevas G, Jimenez-Barbero J. Asensio JL, et al. Among authors: chiara jl. Chem Commun (Camb). 2002 Oct 7;(19):2232-3. doi: 10.1039/b205566j. Chem Commun (Camb). 2002. PMID: 12397992 Free article.

10

Samarium diiodide-mediated reductive coupling of epoxides and carbonyl compounds: a stereocontrolled synthesis of C-glycosides from 1,2-anhydro sugars.

Chiara JL, Sesmilo E. Chiara JL, et al. Angew Chem Int Ed Engl. 2002 Sep 2;41(17):3242-6. doi: 10.1002/1521-3773(20020902)41:17<3242::AID-ANIE3242>3.0.CO;2-I. Angew Chem Int Ed Engl. 2002. PMID: 12207402 No abstract available.

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