Thorel F - Search Results

1

Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity.

Hohl M, Dunand-Sauthier I, Staresincic L, Jaquier-Gubler P, Thorel F, Modesti M, Clarkson SG, Schärer OD. Hohl M, et al. Among authors: thorel f. Nucleic Acids Res. 2007;35(9):3053-63. doi: 10.1093/nar/gkm092. Epub 2007 Apr 22. Nucleic Acids Res. 2007. PMID: 17452369 Free PMC article.

2

Structural determinants for substrate binding and catalysis by the structure-specific endonuclease XPG.

Hohl M, Thorel F, Clarkson SG, Schärer OD. Hohl M, et al. Among authors: thorel f. J Biol Chem. 2003 May 23;278(21):19500-8. doi: 10.1074/jbc.M213155200. Epub 2003 Mar 18. J Biol Chem. 2003. PMID: 12644470 Free article.

3

The spacer region of XPG mediates recruitment to nucleotide excision repair complexes and determines substrate specificity.

Dunand-Sauthier I, Hohl M, Thorel F, Jaquier-Gubler P, Clarkson SG, Schärer OD. Dunand-Sauthier I, et al. Among authors: thorel f. J Biol Chem. 2005 Feb 25;280(8):7030-7. doi: 10.1074/jbc.M412228200. Epub 2004 Dec 7. J Biol Chem. 2005. PMID: 15590680 Free article.

4

The founding members of xeroderma pigmentosum group G produce XPG protein with severely impaired endonuclease activity.

Lalle P, Nouspikel T, Constantinou A, Thorel F, Clarkson SG. Lalle P, et al. Among authors: thorel f. J Invest Dermatol. 2002 Feb;118(2):344-51. doi: 10.1046/j.0022-202x.2001.01673.x. J Invest Dermatol. 2002. PMID: 11841555 Free article.

5

Definition of a short region of XPG necessary for TFIIH interaction and stable recruitment to sites of UV damage.

Thorel F, Constantinou A, Dunand-Sauthier I, Nouspikel T, Lalle P, Raams A, Jaspers NG, Vermeulen W, Shivji MK, Wood RD, Clarkson SG. Thorel F, et al. Mol Cell Biol. 2004 Dec;24(24):10670-80. doi: 10.1128/MCB.24.24.10670-10680.2004. Mol Cell Biol. 2004. PMID: 15572672 Free PMC article.

6

Xeroderma pigmentosum group G with severe neurological involvement and features of Cockayne syndrome in infancy.

Zafeiriou DI, Thorel F, Andreou A, Kleijer WJ, Raams A, Garritsen VH, Gombakis N, Jaspers NG, Clarkson SG. Zafeiriou DI, et al. Among authors: thorel f. Pediatr Res. 2001 Mar;49(3):407-12. doi: 10.1203/00006450-200103000-00016. Pediatr Res. 2001. PMID: 11228268

7

Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development.

Supale S, Thorel F, Merkwirth C, Gjinovci A, Herrera PL, Scorrano L, Meda P, Langer T, Maechler P. Supale S, et al. Among authors: thorel f. Diabetes. 2013 Oct;62(10):3488-99. doi: 10.2337/db13-0152. Epub 2013 Jul 17. Diabetes. 2013. PMID: 23863811 Free PMC article.

8

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas.

Strom A, Bonal C, Ashery-Padan R, Hashimoto N, Campos ML, Trumpp A, Noda T, Kido Y, Real FX, Thorel F, Herrera PL. Strom A, et al. Among authors: thorel f. Development. 2007 Aug;134(15):2719-25. doi: 10.1242/dev.02875. Epub 2007 Jun 27. Development. 2007. PMID: 17596282

9

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss.

Thorel F, Népote V, Avril I, Kohno K, Desgraz R, Chera S, Herrera PL. Thorel F, et al. Nature. 2010 Apr 22;464(7292):1149-54. doi: 10.1038/nature08894. Epub 2010 Apr 4. Nature. 2010. PMID: 20364121 Free PMC article.

10

Stress-induced adaptive islet cell identity changes.

Cigliola V, Thorel F, Chera S, Herrera PL. Cigliola V, et al. Among authors: thorel f. Diabetes Obes Metab. 2016 Sep;18 Suppl 1(Suppl 1):87-96. doi: 10.1111/dom.12726. Diabetes Obes Metab. 2016. PMID: 27615136 Free PMC article. Review.

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