Mermerian AH - Search Results

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Structure-activity relationship, kinetic mechanism, and selectivity for a new class of ubiquitin C-terminal hydrolase-L1 (UCH-L1) inhibitors.

Mermerian AH, Case A, Stein RL, Cuny GD. Mermerian AH, et al. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3729-32. doi: 10.1016/j.bmcl.2007.04.027. Epub 2007 Apr 10. Bioorg Med Chem Lett. 2007. PMID: 17449248

Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator.

Rennie GR, Barden TC, Bernier SG, Carvalho A, Deming R, Germano P, Hudson C, Im GJ, Iyengar RR, Jia L, Jung J, Kim E, Lee TW, Mermerian A, Moore J, Nakai T, Perl NR, Tobin J, Zimmer DP, Renhowe PA. Rennie GR, et al. Bioorg Med Chem Lett. 2021 May 15;40:127886. doi: 10.1016/j.bmcl.2021.127886. Epub 2021 Mar 2. Bioorg Med Chem Lett. 2021. PMID: 33662540

Nucleophile-catalyzed asymmetric acylations of silyl ketene imines: application to the enantioselective synthesis of verapamil.

Mermerian AH, Fu GC. Mermerian AH, et al. Angew Chem Int Ed Engl. 2005 Jan 28;44(6):949-52. doi: 10.1002/anie.200461886. Angew Chem Int Ed Engl. 2005. PMID: 15630710 No abstract available.

Catalytic enantioselective synthesis of quaternary stereocenters via intermolecular C-acylation of silyl ketene acetals: dual activation of the electrophile and the nucleophile.

Mermerian AH, Fu GC. Mermerian AH, et al. J Am Chem Soc. 2003 Apr 9;125(14):4050-1. doi: 10.1021/ja028554k. J Am Chem Soc. 2003. PMID: 12670217

Catalytic enantioselective construction of all-carbon quaternary stereocenters: synthetic and mechanistic studies of the C-acylation of silyl ketene acetals.

Mermerian AH, Fu GC. Mermerian AH, et al. J Am Chem Soc. 2005 Apr 20;127(15):5604-7. doi: 10.1021/ja043832w. J Am Chem Soc. 2005. PMID: 15826199

Metabolism and disposition of MM-433593, a selective FAAH-1 inhibitor, in monkeys.

Banijamali AR, Wakefield JD, Mermerian AH, Busby RW. Banijamali AR, et al. Among authors: mermerian ah. Pharmacol Res Perspect. 2014 Oct;2(5):e00059. doi: 10.1002/prp2.59. Epub 2014 Jul 2. Pharmacol Res Perspect. 2014. PMID: 25505606 Free PMC article.

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