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Malaria-infected mice are cured by oral administration of new artemisinin derivatives.
Posner GH, Chang W, Hess L, Woodard L, Sinishtaj S, Usera AR, Maio W, Rosenthal AS, Kalinda AS, D'Angelo JG, Petersen KS, Stohler R, Chollet J, Santo-Tomas J, Snyder C, Rottmann M, Wittlin S, Brun R, Shapiro TA. Posner GH, et al. Among authors: rosenthal as. J Med Chem. 2008 Feb 28;51(4):1035-42. doi: 10.1021/jm701168h. Epub 2008 Jan 31. J Med Chem. 2008. PMID: 18232653
Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer.
Dexheimer TS, Rosenthal AS, Luci DK, Liang Q, Villamil MA, Chen J, Sun H, Kerns EH, Simeonov A, Jadhav A, Zhuang Z, Maloney DJ. Dexheimer TS, et al. Among authors: rosenthal as. J Med Chem. 2014 Oct 9;57(19):8099-110. doi: 10.1021/jm5010495. Epub 2014 Sep 17. J Med Chem. 2014. PMID: 25229643 Free PMC article.
Discovery of ML323 as a Novel Inhibitor of the USP1/UAF1 Deubiquitinase Complex.
Dexheimer TS, Rosenthal AS, Liang Q, Chen J, Villamil MA, Kerns EH, Simeonov A, Jadhav A, Zhuang Z, Maloney DJ. Dexheimer TS, et al. Among authors: rosenthal as. 2012 Oct 23 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Oct 23 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 25506968 Free Books & Documents. Review.
120 results