Wu X - Search Results

1

Identification of the major metabolites of 5-n-butyl-4-{4-[2-(1H-tetrazole-5-yl)-1H-pyrrol-1-yl]phenylmethyl}-2,4-dihydro-2-(2,6-dichloridephenyl)-3H-1,2,4-triazol-3-one, a new angiotensin type 1 receptor antagonist, in rat bile by HPLC-diode array detection-MS and HPLC-MS/MS.

Yan B, Wang G, Sun J, Li X, Zheng Y, Ai H, Lv H, Wu X, Xu J. Yan B, et al. Among authors: wu x. Biomed Chromatogr. 2007 Sep;21(9):912-24. doi: 10.1002/bmc.822. Biomed Chromatogr. 2007. PMID: 17428010

2

Structural elucidation of impurities in 5-n-butyl-4-{4-[2-(1H-tetrazole-5-yl)-1H-pyrrol-1-yl]phenylmethyl}-2,4-dihydro-2-(2,6-dichlorophenyl)-3H-1,2,4-triazol-3-one (Ib), a novel nonpeptide angiotensin AT1 receptor antagonist.

Gao T, Liu Y, Ji Y, Wu X, Xu J. Gao T, et al. Among authors: wu x. J Pharm Biomed Anal. 2012 Jul;66:381-6. doi: 10.1016/j.jpba.2012.03.031. Epub 2012 Mar 31. J Pharm Biomed Anal. 2012. PMID: 22516679

3

[Ca2+]i and PKC-alpha are involved in the inhibitory effects of Ib, a novel nonpeptide AngiotensinII subtype AT1 receptor antagonist, on AngiotensinII-induced vascular contraction in vitro.

Wang Y, Wang W, Wang Q, Wu J, Xu J, Wu X. Wang Y, et al. Among authors: wu x, wu j. Biochem Biophys Res Commun. 2007 Dec 7;364(1):118-23. doi: 10.1016/j.bbrc.2007.09.101. Epub 2007 Oct 1. Biochem Biophys Res Commun. 2007. PMID: 17931598

4

Characterization of angiotensin II antagonism displayed by Ib, a novel nonpeptide angiotensin AT(1) receptor antagonist.

Wu J, Wang Q, Guo J, Hu Z, Yin Z, Xu J, Wu X. Wu J, et al. Among authors: wu x. Eur J Pharmacol. 2008 Jul 28;589(1-3):220-4. doi: 10.1016/j.ejphar.2008.05.007. Epub 2008 May 20. Eur J Pharmacol. 2008. PMID: 18571160

5

PKC-dependent extracellular signal-regulated kinase 1/2 pathway is involved in the inhibition of Ib on AngiotensinII-induced proliferation of vascular smooth muscle cells.

Wang Y, Yan T, Wang Q, Wang W, Xu J, Wu X, Ji H. Wang Y, et al. Among authors: wu x. Biochem Biophys Res Commun. 2008 Oct 10;375(1):151-5. doi: 10.1016/j.bbrc.2008.07.137. Epub 2008 Aug 5. Biochem Biophys Res Commun. 2008. PMID: 18687307

6

Synthesis and biological evaluation of 4'-[(benzimidazole-1-yl)methyl]biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists.

Bai R, Wei Z, Liu J, Xie W, Yao H, Wu X, Jiang J, Wang Q, Xu J. Bai R, et al. Among authors: wu x. Bioorg Med Chem. 2012 Aug 1;20(15):4661-7. doi: 10.1016/j.bmc.2012.06.011. Epub 2012 Jun 15. Bioorg Med Chem. 2012. PMID: 22750010

7

Design, synthesis, and biological evaluation of 1,2,4-triazole bearing 5-substituted biphenyl-2-sulfonamide derivatives as potential antihypertensive candidates.

Liu J, Liu Q, Yang X, Xu S, Zhang H, Bai R, Yao H, Jiang J, Shen M, Wu X, Xu J. Liu J, et al. Among authors: wu x. Bioorg Med Chem. 2013 Dec 15;21(24):7742-51. doi: 10.1016/j.bmc.2013.10.017. Epub 2013 Oct 23. Bioorg Med Chem. 2013. PMID: 24200932

8

XJP-1, a novel ACEI, with anti-inflammatory properties in HUVECs.

Fu R, Chen Z, Wang Q, Guo Q, Xu J, Wu X. Fu R, et al. Among authors: wu x. Atherosclerosis. 2011 Nov;219(1):40-8. doi: 10.1016/j.atherosclerosis.2011.07.010. Epub 2011 Jul 20. Atherosclerosis. 2011. PMID: 21803355

9

XJP-1 protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by inhibiting NADPH oxidase subunit expression and modulating the PI3K/Akt/eNOS pathway.

Fu R, Wang Q, Guo Q, Xu J, Wu X. Fu R, et al. Among authors: wu x. Vascul Pharmacol. 2013 Jan;58(1-2):78-86. doi: 10.1016/j.vph.2012.08.004. Epub 2012 Aug 23. Vascul Pharmacol. 2013. PMID: 22980246

10

Current natural products with antihypertensive activity.

Bai RR, Wu XM, Xu JY. Bai RR, et al. Chin J Nat Med. 2015 Oct;13(10):721-9. doi: 10.1016/S1875-5364(15)30072-8. Chin J Nat Med. 2015. PMID: 26481372 Review.

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