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The tumor suppressor CYLD regulates entry into mitosis.
Stegmeier F, Sowa ME, Nalepa G, Gygi SP, Harper JW, Elledge SJ. Stegmeier F, et al. Proc Natl Acad Sci U S A. 2007 May 22;104(21):8869-74. doi: 10.1073/pnas.0703268104. Epub 2007 May 10. Proc Natl Acad Sci U S A. 2007. PMID: 17495026 Free PMC article.
Dissecting cancer pathways and vulnerabilities with RNAi.
Westbrook TF, Stegmeier F, Elledge SJ. Westbrook TF, et al. Among authors: stegmeier f. Cold Spring Harb Symp Quant Biol. 2005;70:435-44. doi: 10.1101/sqb.2005.70.031. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869781 Review.
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling.
Huang SM, Mishina YM, Liu S, Cheung A, Stegmeier F, Michaud GA, Charlat O, Wiellette E, Zhang Y, Wiessner S, Hild M, Shi X, Wilson CJ, Mickanin C, Myer V, Fazal A, Tomlinson R, Serluca F, Shao W, Cheng H, Shultz M, Rau C, Schirle M, Schlegl J, Ghidelli S, Fawell S, Lu C, Curtis D, Kirschner MW, Lengauer C, Finan PM, Tallarico JA, Bouwmeester T, Porter JA, Bauer A, Cong F. Huang SM, et al. Among authors: stegmeier f. Nature. 2009 Oct 1;461(7264):614-20. doi: 10.1038/nature08356. Epub 2009 Sep 16. Nature. 2009. PMID: 19759537
41 results