Nakada MT - Search Results

1

Phase I evaluation of a fully human anti-alphav integrin monoclonal antibody (CNTO 95) in patients with advanced solid tumors.

Mullamitha SA, Ton NC, Parker GJ, Jackson A, Julyan PJ, Roberts C, Buonaccorsi GA, Watson Y, Davies K, Cheung S, Hope L, Valle JW, Radford JA, Lawrance J, Saunders MP, Munteanu MC, Nakada MT, Nemeth JA, Davis HM, Jiao Q, Prabhakar U, Lang Z, Corringham RE, Beckman RA, Jayson GC. Mullamitha SA, et al. Among authors: nakada mt. Clin Cancer Res. 2007 Apr 1;13(7):2128-35. doi: 10.1158/1078-0432.CCR-06-2779. Clin Cancer Res. 2007. PMID: 17404096 Clinical Trial.

2

CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo.

Trikha M, Zhou Z, Nemeth JA, Chen Q, Sharp C, Emmell E, Giles-Komar J, Nakada MT. Trikha M, et al. Among authors: nakada mt. Int J Cancer. 2004 Jun 20;110(3):326-35. doi: 10.1002/ijc.20116. Int J Cancer. 2004. PMID: 15095296

3

Alpha-v integrins as therapeutic targets in oncology.

Nemeth JA, Nakada MT, Trikha M, Lang Z, Gordon MS, Jayson GC, Corringham R, Prabhakar U, Davis HM, Beckman RA. Nemeth JA, et al. Among authors: nakada mt. Cancer Invest. 2007 Oct;25(7):632-46. doi: 10.1080/07357900701522638. Cancer Invest. 2007. PMID: 18027153 Review.

4

A clinical study assessing the tolerability and biological effects of infliximab, a TNF-alpha inhibitor, in patients with advanced cancer.

Brown ER, Charles KA, Hoare SA, Rye RL, Jodrell DI, Aird RE, Vora R, Prabhakar U, Nakada M, Corringham RE, DeWitte M, Sturgeon C, Propper D, Balkwill FR, Smyth JF. Brown ER, et al. Ann Oncol. 2008 Jul;19(7):1340-1346. doi: 10.1093/annonc/mdn054. Epub 2008 Mar 5. Ann Oncol. 2008. PMID: 18325912 Free article. Clinical Trial.

5

Alphav integrin-targeted immunoconjugates regress established human tumors in xenograft models.

Chen Q, Millar HJ, McCabe FL, Manning CD, Steeves R, Lai K, Kellogg B, Lutz RJ, Trikha M, Nakada MT, Anderson GM. Chen Q, et al. Among authors: nakada mt. Clin Cancer Res. 2007 Jun 15;13(12):3689-95. doi: 10.1158/1078-0432.CCR-07-0026. Clin Cancer Res. 2007. PMID: 17575234

6

Regulation of growth of prostate cancer cells selected in the presence of interleukin-6 by the anti-interleukin-6 antibody CNTO 328.

Steiner H, Cavarretta IT, Moser PL, Berger AP, Bektic J, Dietrich H, Zaki MH, Nakada M, Hobisch A, Nemeth JA, Culig Z. Steiner H, et al. Prostate. 2006 Dec 1;66(16):1744-52. doi: 10.1002/pros.20492. Prostate. 2006. PMID: 16998813

7

CNTO 95, a fully human anti alphav integrin antibody, inhibits cell signaling, migration, invasion, and spontaneous metastasis of human breast cancer cells.

Chen Q, Manning CD, Millar H, McCabe FL, Ferrante C, Sharp C, Shahied-Arruda L, Doshi P, Nakada MT, Anderson GM. Chen Q, et al. Among authors: nakada mt. Clin Exp Metastasis. 2008;25(2):139-48. doi: 10.1007/s10585-007-9132-4. Epub 2007 Dec 5. Clin Exp Metastasis. 2008. PMID: 18064530

8

CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models.

Ngo CV, Picha K, McCabe F, Millar H, Tawadros R, Tam SH, Nakada MT, Anderson GM. Ngo CV, et al. Among authors: nakada mt. Int J Cancer. 2007 Mar 15;120(6):1261-7. doi: 10.1002/ijc.22426. Int J Cancer. 2007. PMID: 17192924

9

Multiple roles for platelet GPIIb/IIIa and alphavbeta3 integrins in tumor growth, angiogenesis, and metastasis.

Trikha M, Zhou Z, Timar J, Raso E, Kennel M, Emmell E, Nakada MT. Trikha M, et al. Among authors: nakada mt. Cancer Res. 2002 May 15;62(10):2824-33. Cancer Res. 2002. PMID: 12019160

10

Platelets and cancer: implications for antiangiogenic therapy.

Trikha M, Nakada MT. Trikha M, et al. Among authors: nakada mt. Semin Thromb Hemost. 2002 Feb;28(1):39-44. doi: 10.1055/s-2002-20563. Semin Thromb Hemost. 2002. PMID: 11885024 Review.

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