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Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: implications for the role of nitration in the progression of Alzheimer's disease.
Butterfield DA, Reed TT, Perluigi M, De Marco C, Coccia R, Keller JN, Markesbery WR, Sultana R. Butterfield DA, et al. Among authors: perluigi m. Brain Res. 2007 May 7;1148:243-8. doi: 10.1016/j.brainres.2007.02.084. Epub 2007 Mar 7. Brain Res. 2007. PMID: 17395167 Free PMC article.
Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer's Disease-like Neuropathology in a Mouse Model for Down Syndrome.
Tramutola A, Lanzillotta S, Aceto G, Pagnotta S, Ruffolo G, Cifelli P, Marini F, Ripoli C, Palma E, Grassi C, Di Domenico F, Perluigi M, Barone E. Tramutola A, et al. Among authors: perluigi m. Antioxidants (Basel). 2023 Jan 2;12(1):111. doi: 10.3390/antiox12010111. Antioxidants (Basel). 2023. PMID: 36670973 Free PMC article.
Altered mitochondrial unfolded protein response and protein quality control promote oxidative distress in down syndrome brain.
Lanzillotta S, Esteve D, Lanzillotta C, Tramutola A, Lloret A, Forte E, Pesce V, Picca A, Di Domenico F, Perluigi M, Barone E. Lanzillotta S, et al. Among authors: perluigi m. Free Radic Biol Med. 2024 Nov 23;227:80-93. doi: 10.1016/j.freeradbiomed.2024.11.043. Online ahead of print. Free Radic Biol Med. 2024. PMID: 39586382 Free article.
Chronic treatment with the anti-diabetic drug metformin rescues impaired brain mitochondrial activity and selectively ameliorates defective cognitive flexibility in a female mouse model of Rett syndrome.
Urbinati C, Lanzillotta C, Cosentino L, Valenti D, Quattrini MC, Di Crescenzo L, Prestia F, Pietraforte D, Perluigi M, Di Domenico F, Vacca RA, De Filippis B. Urbinati C, et al. Among authors: perluigi m. Neuropharmacology. 2023 Feb 15;224:109350. doi: 10.1016/j.neuropharm.2022.109350. Epub 2022 Nov 25. Neuropharmacology. 2023. PMID: 36442649
Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome.
Giallongo S, Ferrigno J, Caltabiano R, Broggi G, Alanazi AM, Distefano A, Tropea E, Tramutola A, Perluigi M, Volti GL, Barone E, Barbagallo IA. Giallongo S, et al. Among authors: perluigi m. Aging (Albany NY). 2024 Jun 26;16(12):10203-10215. doi: 10.18632/aging.205970. Epub 2024 Jun 26. Aging (Albany NY). 2024. PMID: 38942607 Free PMC article.
149 results