Loetscher P - Search Results

1

The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice.

Ninichuk V, Khandoga AG, Segerer S, Loetscher P, Schlapbach A, Revesz L, Feifel R, Khandoga A, Krombach F, Nelson PJ, Schlöndorff D, Anders HJ. Ninichuk V, et al. Among authors: loetscher p. Am J Pathol. 2007 Apr;170(4):1267-76. doi: 10.2353/ajpath.2007.060937. Am J Pathol. 2007. PMID: 17392166 Free PMC article.

2

Microinjection of Cre recombinase protein into zygotes enables specific deletion of two eukaryotic selection cassettes and enhances the expression of a DsRed2 reporter gene in Ccr2/Ccr5 double-deficient mice.

Luckow B, Hänggli A, Maier H, Chilla S, Loewe RP, Dehmel S, Schlöndorff D, Loetscher P, Zerwes HG, Müller M. Luckow B, et al. Among authors: loetscher p. Genesis. 2009 Aug;47(8):545-58. doi: 10.1002/dvg.20531. Genesis. 2009. PMID: 19517561

3

Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis.

Revesz L, Bollbuck B, Buhl T, Eder J, Esser R, Feifel R, Heng R, Hiestand P, Jachez-Demange B, Loetscher P, Sparrer H, Schlapbach A, Waelchli R. Revesz L, et al. Among authors: loetscher p. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5160-4. doi: 10.1016/j.bmcl.2005.08.057. Epub 2005 Sep 28. Bioorg Med Chem Lett. 2005. PMID: 16198561

4

Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model.

Kitamura T, Fujishita T, Loetscher P, Revesz L, Hashida H, Kizaka-Kondoh S, Aoki M, Taketo MM. Kitamura T, et al. Among authors: loetscher p. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13063-8. doi: 10.1073/pnas.1002372107. Epub 2010 Jun 29. Proc Natl Acad Sci U S A. 2010. PMID: 20616008 Free PMC article.

5

Monocyte chemoattractant protein-1 gene expression in prostatic hyperplasia and prostate adenocarcinoma.

Mazzucchelli L, Loetscher P, Kappeler A, Uguccioni M, Baggiolini M, Laissue JA, Mueller C. Mazzucchelli L, et al. Among authors: loetscher p. Am J Pathol. 1996 Aug;149(2):501-9. Am J Pathol. 1996. PMID: 8701989 Free PMC article.

6

Design and synthesis of potent and orally active GPR4 antagonists with modulatory effects on nociception, inflammation, and angiogenesis.

Miltz W, Velcicky J, Dawson J, Littlewood-Evans A, Ludwig MG, Seuwen K, Feifel R, Oberhauser B, Meyer A, Gabriel D, Nash M, Loetscher P. Miltz W, et al. Among authors: loetscher p. Bioorg Med Chem. 2017 Aug 15;25(16):4512-4525. doi: 10.1016/j.bmc.2017.06.050. Epub 2017 Jun 29. Bioorg Med Chem. 2017. PMID: 28689977

7

Development of Selective, Orally Active GPR4 Antagonists with Modulatory Effects on Nociception, Inflammation, and Angiogenesis.

Velcicky J, Miltz W, Oberhauser B, Orain D, Vaupel A, Weigand K, Dawson King J, Littlewood-Evans A, Nash M, Feifel R, Loetscher P. Velcicky J, et al. Among authors: loetscher p. J Med Chem. 2017 May 11;60(9):3672-3683. doi: 10.1021/acs.jmedchem.6b01703. Epub 2017 Apr 26. J Med Chem. 2017. PMID: 28445047

8

Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition Assay.

Knoepfel T, Nimsgern P, Jacquier S, Bourrel M, Vangrevelinghe E, Glatthar R, Behnke D, Alper PB, Michellys PY, Deane J, Junt T, Zipfel G, Limonta S, Hawtin S, Andre C, Boulay T, Loetscher P, Faller M, Blank J, Feifel R, Betschart C. Knoepfel T, et al. Among authors: loetscher p. J Med Chem. 2020 Aug 13;63(15):8276-8295. doi: 10.1021/acs.jmedchem.0c00130. Epub 2020 Jul 30. J Med Chem. 2020. PMID: 32786235

9

Inverse MCP-1/IL-8 ratio in effluents of CAPD patients with peritonitis and in isolated cultured human peritoneal macrophages.

Sach M, Bauermeister K, Burger JA, Loetscher P, Elsner J, Schollmeyer P, Dobos GJ. Sach M, et al. Among authors: loetscher p. Nephrol Dial Transplant. 1997 Feb;12(2):315-20. doi: 10.1093/ndt/12.2.315. Nephrol Dial Transplant. 1997. PMID: 9132652

10

CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.

Bignon A, Gaudin F, Hémon P, Tharinger H, Mayol K, Walzer T, Loetscher P, Peuchmaur M, Berrebi D, Balabanian K. Bignon A, et al. Among authors: loetscher p. J Immunol. 2014 Feb 1;192(3):886-96. doi: 10.4049/jimmunol.1300123. Epub 2013 Dec 23. J Immunol. 2014. PMID: 24367031

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