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Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes.
McConnell O, Bach A 2nd, Balibar C, Byrne N, Cai Y, Carter G, Chlenov M, Di L, Fan K, Goljer I, He Y, Herold D, Kagan M, Kerns E, Koehn F, Kraml C, Marathias V, Marquez B, McDonald L, Nogle L, Petucci C, Schlingmann G, Tawa G, Tischler M, Williamson RT, Sutherland A, Watts W, Young M, Zhang MY, Zhang Y, Zhou D, Ho D. McConnell O, et al. Among authors: zhang my, zhang y. Chirality. 2007 Sep;19(9):658-82. doi: 10.1002/chir.20399. Chirality. 2007. PMID: 17390370 Review.
Integrity profiling of high throughput screening hits using LC-MS and related techniques.
Kerns EH, Di L, Bourassa J, Gross J, Huang N, Liu H, Kleintop T, Nogle L, Mallis L, Petucci C, Petusky S, Tischler M, Sabus C, Sarkahian A, Young M, Zhang MY, Huryn D, McConnell O, Carter G. Kerns EH, et al. Among authors: zhang my. Comb Chem High Throughput Screen. 2005 Sep;8(6):459-66. doi: 10.2174/1386207054867283. Comb Chem High Throughput Screen. 2005. PMID: 16178805 Review.
The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists.
Childers WE Jr, Havran LM, Asselin M, Bicksler JJ, Chong DC, Grosu GT, Shen Z, Abou-Gharbia MA, Bach AC 3rd, Harrison BL, Kagan N, Kleintop T, Magolda R, Marathias V, Robichaud AJ, Sabb AL, Zhang MY, Andree TH, Aschmies SH, Beyer C, Comery TA, Day M, Grauer SM, Hughes ZA, Rosenzweig-Lipson S, Platt B, Pulicicchio C, Smith DE, Sukoff-Rizzo SJ, Sullivan KM, Adedoyin A, Huselton C, Hirst WD. Childers WE Jr, et al. Among authors: zhang my. J Med Chem. 2010 May 27;53(10):4066-84. doi: 10.1021/jm1000908. J Med Chem. 2010. PMID: 20443629
1,158 results