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Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery: building chiral technology toolboxes.
McConnell O, Bach A 2nd, Balibar C, Byrne N, Cai Y, Carter G, Chlenov M, Di L, Fan K, Goljer I, He Y, Herold D, Kagan M, Kerns E, Koehn F, Kraml C, Marathias V, Marquez B, McDonald L, Nogle L, Petucci C, Schlingmann G, Tawa G, Tischler M, Williamson RT, Sutherland A, Watts W, Young M, Zhang MY, Zhang Y, Zhou D, Ho D. McConnell O, et al. Among authors: goljer i. Chirality. 2007 Sep;19(9):658-82. doi: 10.1002/chir.20399. Chirality. 2007. PMID: 17390370 Review.
Metabolism of intravenous methylnaltrexone in mice, rats, dogs, and humans.
Chandrasekaran A, Tong Z, Li H, Erve JC, DeMaio W, Goljer I, McConnell O, Rotshteyn Y, Hultin T, Talaat R, Scatina J. Chandrasekaran A, et al. Among authors: goljer i. Drug Metab Dispos. 2010 Apr;38(4):606-16. doi: 10.1124/dmd.109.031179. Epub 2010 Jan 6. Drug Metab Dispos. 2010. PMID: 20053817 Clinical Trial.
Modulation of Wnt signaling through inhibition of secreted frizzled-related protein I (sFRP-1) with N-substituted piperidinyl diphenylsulfonyl sulfonamides.
Moore WJ, Kern JC, Bhat R, Commons TJ, Fukayama S, Goljer I, Krishnamurthy G, Magolda RL, Nogle L, Pitts K, Stauffer B, Trybulski EJ, Welmaker GS, Wilson M, Bodine PV. Moore WJ, et al. Among authors: goljer i. J Med Chem. 2009 Jan 8;52(1):105-16. doi: 10.1021/jm801144h. J Med Chem. 2009. PMID: 19072540
28 results