Spooner E - Search Results

1

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.

Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM. Sancak Y, et al. Among authors: spooner e. Mol Cell. 2007 Mar 23;25(6):903-15. doi: 10.1016/j.molcel.2007.03.003. Mol Cell. 2007. PMID: 17386266 Free article.

2

Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism.

Chen CH, Kiyan V, Zhylkibayev AA, Kazyken D, Bulgakova O, Page KE, Bersimbaev RI, Spooner E, Sarbassov DD. Chen CH, et al. Among authors: spooner e. J Biol Chem. 2013 Sep 20;288(38):27019-27030. doi: 10.1074/jbc.M113.498055. Epub 2013 Aug 8. J Biol Chem. 2013. PMID: 23928304 Free PMC article.

3

The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

Tsun ZY, Bar-Peled L, Chantranupong L, Zoncu R, Wang T, Kim C, Spooner E, Sabatini DM. Tsun ZY, et al. Among authors: spooner e. Mol Cell. 2013 Nov 21;52(4):495-505. doi: 10.1016/j.molcel.2013.09.016. Epub 2013 Oct 3. Mol Cell. 2013. PMID: 24095279 Free PMC article.

4

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.

Chantranupong L, Wolfson RL, Orozco JM, Saxton RA, Scaria SM, Bar-Peled L, Spooner E, Isasa M, Gygi SP, Sabatini DM. Chantranupong L, et al. Among authors: spooner e. Cell Rep. 2014 Oct 9;9(1):1-8. doi: 10.1016/j.celrep.2014.09.014. Epub 2014 Sep 25. Cell Rep. 2014. PMID: 25263562 Free PMC article.

5

Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection.

Misaghi S, Balsara ZR, Catic A, Spooner E, Ploegh HL, Starnbach MN. Misaghi S, et al. Among authors: spooner e. Mol Microbiol. 2006 Jul;61(1):142-50. doi: 10.1111/j.1365-2958.2006.05199.x. Mol Microbiol. 2006. PMID: 16824101 Free article.

6

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.

Brinkmann MM, Spooner E, Hoebe K, Beutler B, Ploegh HL, Kim YM. Brinkmann MM, et al. Among authors: spooner e. J Cell Biol. 2007 Apr 23;177(2):265-75. doi: 10.1083/jcb.200612056. J Cell Biol. 2007. PMID: 17452530 Free PMC article.

7

SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins.

Mueller B, Klemm EJ, Spooner E, Claessen JH, Ploegh HL. Mueller B, et al. Among authors: spooner e. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12325-30. doi: 10.1073/pnas.0805371105. Epub 2008 Aug 18. Proc Natl Acad Sci U S A. 2008. PMID: 18711132 Free PMC article.

8

A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae.

Kattenhorn LM, Korbel GA, Kessler BM, Spooner E, Ploegh HL. Kattenhorn LM, et al. Among authors: spooner e. Mol Cell. 2005 Aug 19;19(4):547-57. doi: 10.1016/j.molcel.2005.07.003. Mol Cell. 2005. PMID: 16109378 Free article.

9

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M, Shi Y. Whetstine JR, et al. Among authors: spooner e. Cell. 2006 May 5;125(3):467-81. doi: 10.1016/j.cell.2006.03.028. Epub 2006 Apr 6. Cell. 2006. PMID: 16603238 Free article.

10

Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum.

Artavanis-Tsakonas K, Misaghi S, Comeaux CA, Catic A, Spooner E, Duraisingh MT, Ploegh HL. Artavanis-Tsakonas K, et al. Among authors: spooner e. Mol Microbiol. 2006 Sep;61(5):1187-95. doi: 10.1111/j.1365-2958.2006.05307.x. Mol Microbiol. 2006. PMID: 16925553 Free PMC article.

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