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Page 1
Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.
Kirkland TA, Adler M, Bauman JG, Chen M, Haeggström JZ, King B, Kochanny MJ, Liang AM, Mendoza L, Phillips GB, Thunnissen M, Trinh L, Whitlow M, Ye B, Ye H, Parkinson J, Guilford WJ. Kirkland TA, et al. Bioorg Med Chem. 2008 May 1;16(9):4963-83. doi: 10.1016/j.bmc.2008.03.042. Epub 2008 Mar 20. Bioorg Med Chem. 2008. PMID: 18394906
Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.
Ye B, Bauman J, Chen M, Davey D, Khim SK, King B, Kirkland T, Kochanny M, Liang A, Lentz D, May K, Mendoza L, Phillips G, Selchau V, Schlyer S, Tseng JL, Wei RG, Ye H, Parkinson J, Guilford WJ. Ye B, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3891-4. doi: 10.1016/j.bmcl.2008.06.046. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18586492
Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors.
Khim SK, Bauman J, Evans J, Freeman B, King B, Kirkland T, Kochanny M, Lentz D, Liang A, Mendoza L, Phillips G, Tseng JL, Wei RG, Ye H, Yu L, Parkinson J, Guilford WJ. Khim SK, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3895-8. doi: 10.1016/j.bmcl.2008.06.041. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18590959
Second-generation beta-oxidation resistant 3-oxa-lipoxin A4 analogs.
Guilford WJ, Parkinson JF. Guilford WJ, et al. Among authors: parkinson jf. Prostaglandins Leukot Essent Fatty Acids. 2005 Sep-Oct;73(3-4):245-50. doi: 10.1016/j.plefa.2005.05.012. Prostaglandins Leukot Essent Fatty Acids. 2005. PMID: 15985364 Review.
Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors.
Davey DD, Adler M, Arnaiz D, Eagen K, Erickson S, Guilford W, Kenrick M, Morrissey MM, Ohlmeyer M, Pan G, Paradkar VM, Parkinson J, Polokoff M, Saionz K, Santos C, Subramanyam B, Vergona R, Wei RG, Whitlow M, Ye B, Zhao ZS, Devlin JJ, Phillips G. Davey DD, et al. J Med Chem. 2007 Mar 22;50(6):1146-57. doi: 10.1021/jm061319i. Epub 2007 Feb 23. J Med Chem. 2007. PMID: 17315988
Differential inhibition of inducible T cell cytokine secretion by potent iron chelators.
Leung S, Holbrook A, King B, Lu HT, Evans V, Miyamoto N, Mallari C, Harvey S, Davey D, Ho E, Li WW, Parkinson J, Horuk R, Jaroch S, Berger M, Skuballa W, West C, Pulk R, Phillips G, Bryant J, Subramanyam B, Schaefer C, Salamon H, Lyons E, Schilling D, Seidel H, Kraetzschmar J, Snider M, Perez D. Leung S, et al. J Biomol Screen. 2005 Mar;10(2):157-67. doi: 10.1177/1087057104272394. J Biomol Screen. 2005. PMID: 15799959
84 results