Pei Y - Search Results

1

Structural biology of RNA silencing and its functional implications.

Patel DJ, Ma JB, Yuan YR, Ye K, Pei Y, Kuryavyi V, Malinina L, Meister G, Tuschl T. Patel DJ, et al. Among authors: pei y. Cold Spring Harb Symp Quant Biol. 2006;71:81-93. doi: 10.1101/sqb.2006.71.053. Cold Spring Harb Symp Quant Biol. 2006. PMID: 17381284 Free PMC article. Review.

2

Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.

Ma JB, Yuan YR, Meister G, Pei Y, Tuschl T, Patel DJ. Ma JB, et al. Among authors: pei y. Nature. 2005 Mar 31;434(7033):666-70. doi: 10.1038/nature03514. Nature. 2005. PMID: 15800629 Free PMC article.

3

Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage.

Yuan YR, Pei Y, Ma JB, Kuryavyi V, Zhadina M, Meister G, Chen HY, Dauter Z, Tuschl T, Patel DJ. Yuan YR, et al. Among authors: pei y. Mol Cell. 2005 Aug 5;19(3):405-19. doi: 10.1016/j.molcel.2005.07.011. Mol Cell. 2005. PMID: 16061186 Free PMC article.

4

A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA.

Yuan YR, Pei Y, Chen HY, Tuschl T, Patel DJ. Yuan YR, et al. Among authors: pei y. Structure. 2006 Oct;14(10):1557-65. doi: 10.1016/j.str.2006.08.009. Structure. 2006. PMID: 17027504 Free PMC article.

5

On the art of identifying effective and specific siRNAs.

Pei Y, Tuschl T. Pei Y, et al. Nat Methods. 2006 Sep;3(9):670-6. doi: 10.1038/nmeth911. Nat Methods. 2006. PMID: 16929310 Review.

6

Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity.

Chen PY, Weinmann L, Gaidatzis D, Pei Y, Zavolan M, Tuschl T, Meister G. Chen PY, et al. Among authors: pei y. RNA. 2008 Feb;14(2):263-74. doi: 10.1261/rna.789808. Epub 2007 Dec 19. RNA. 2008. PMID: 18094121 Free PMC article.

7

Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense.

Zhang X, Yuan YR, Pei Y, Lin SS, Tuschl T, Patel DJ, Chua NH. Zhang X, et al. Among authors: pei y. Genes Dev. 2006 Dec 1;20(23):3255-68. doi: 10.1101/gad.1495506. Genes Dev. 2006. PMID: 17158744 Free PMC article.

8

Systematic chemical modifications of single stranded siRNAs significantly improved CTNNB1 mRNA silencing.

Chang W, Pei Y, Guidry EN, Zewge D, Parish CA, Sherer EC, DiMuzio J, Zhang H, South VJ, Strapps WR, Sepp-Lorenzino L, Colletti SL, Stanton MG. Chang W, et al. Among authors: pei y. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4513-4517. doi: 10.1016/j.bmcl.2016.07.064. Epub 2016 Jul 28. Bioorg Med Chem Lett. 2016. PMID: 27503684

9

RNA-induced silencing complex-bound small interfering RNA is a determinant of RNA interference-mediated gene silencing in mice.

Wei J, Jones J, Kang J, Card A, Krimm M, Hancock P, Pei Y, Ason B, Payson E, Dubinina N, Cancilla M, Stroh M, Burchard J, Sachs AB, Hochman JH, Flanagan WM, Kuklin NA. Wei J, et al. Among authors: pei y. Mol Pharmacol. 2011 Jun;79(6):953-63. doi: 10.1124/mol.110.070409. Epub 2011 Mar 22. Mol Pharmacol. 2011. PMID: 21427169

10

Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape.

Bartz R, Fan H, Zhang J, Innocent N, Cherrin C, Beck SC, Pei Y, Momose A, Jadhav V, Tellers DM, Meng F, Crocker LS, Sepp-Lorenzino L, Barnett SF. Bartz R, et al. Among authors: pei y. Biochem J. 2011 Apr 15;435(2):475-87. doi: 10.1042/BJ20101021. Biochem J. 2011. PMID: 21265735

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