Sombati S - Search Results

1

Aging is associated with elevated intracellular calcium levels and altered calcium homeostatic mechanisms in hippocampal neurons.

Raza M, Deshpande LS, Blair RE, Carter DS, Sombati S, DeLorenzo RJ. Raza M, et al. Among authors: sombati s. Neurosci Lett. 2007 May 11;418(1):77-81. doi: 10.1016/j.neulet.2007.03.005. Epub 2007 Mar 12. Neurosci Lett. 2007. PMID: 17374449 Free PMC article.

2

In vitro inhibition of pentylenetetrazole and bicuculline-induced epileptiform activity in rat hippocampal pyramidal neurons by aqueous fraction isolated from Delphinium denudatum.

Raza M, Shaheen F, Choudhary MI, Rahman AU, Sombati S, DeLorenzo RJ. Raza M, et al. Among authors: sombati s. Neurosci Lett. 2002 Nov 22;333(2):103-6. doi: 10.1016/s0304-3940(02)01027-3. Neurosci Lett. 2002. PMID: 12419491

3

Calcium-dependent epileptogenesis in an in vitro model of stroke-induced "epilepsy".

Sun DA, Sombati S, Blair RE, DeLorenzo RJ. Sun DA, et al. Among authors: sombati s. Epilepsia. 2002 Nov;43(11):1296-305. doi: 10.1046/j.1528-1157.2002.09702.x. Epilepsia. 2002. PMID: 12423378 Free article.

4

Epileptogenesis causes acute and chronic increases in GABAA receptor endocytosis that contributes to the induction and maintenance of seizures in the hippocampal culture model of acquired epilepsy.

Blair RE, Sombati S, Lawrence DC, McCay BD, DeLorenzo RJ. Blair RE, et al. Among authors: sombati s. J Pharmacol Exp Ther. 2004 Sep;310(3):871-80. doi: 10.1124/jpet.104.068478. Epub 2004 Apr 14. J Pharmacol Exp Ther. 2004. PMID: 15084648

5

Evidence that injury-induced changes in hippocampal neuronal calcium dynamics during epileptogenesis cause acquired epilepsy.

Raza M, Blair RE, Sombati S, Carter DS, Deshpande LS, DeLorenzo RJ. Raza M, et al. Among authors: sombati s. Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17522-7. doi: 10.1073/pnas.0408155101. Epub 2004 Dec 6. Proc Natl Acad Sci U S A. 2004. PMID: 15583136 Free PMC article.

6

Altered calcium/calmodulin kinase II activity changes calcium homeostasis that underlies epileptiform activity in hippocampal neurons in culture.

Carter DS, Haider SN, Blair RE, Deshpande LS, Sombati S, DeLorenzo RJ. Carter DS, et al. Among authors: sombati s. J Pharmacol Exp Ther. 2006 Dec;319(3):1021-31. doi: 10.1124/jpet.106.110403. Epub 2006 Sep 13. J Pharmacol Exp Ther. 2006. PMID: 16971505

7

Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy.

Deshpande LS, Sombati S, Blair RE, Carter DS, Martin BR, DeLorenzo RJ. Deshpande LS, et al. Among authors: sombati s. Neurosci Lett. 2007 Jan 3;411(1):11-6. doi: 10.1016/j.neulet.2006.09.046. Epub 2006 Nov 15. Neurosci Lett. 2007. PMID: 17110038 Free PMC article.

8

Endocannabinoids block status epilepticus in cultured hippocampal neurons.

Deshpande LS, Blair RE, Ziobro JM, Sombati S, Martin BR, DeLorenzo RJ. Deshpande LS, et al. Among authors: sombati s. Eur J Pharmacol. 2007 Mar 8;558(1-3):52-9. doi: 10.1016/j.ejphar.2006.11.030. Epub 2006 Nov 22. Eur J Pharmacol. 2007. PMID: 17174949 Free PMC article.

9

Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus.

Deshpande LS, Blair RE, Nagarkatti N, Sombati S, Martin BR, DeLorenzo RJ. Deshpande LS, et al. Among authors: sombati s. Exp Neurol. 2007 Apr;204(2):705-13. doi: 10.1016/j.expneurol.2007.01.001. Epub 2007 Jan 9. Exp Neurol. 2007. PMID: 17289026 Free PMC article.

10

Activation of a novel injury-induced calcium-permeable channel that plays a key role in causing extended neuronal depolarization and initiating neuronal death in excitotoxic neuronal injury.

Deshpande LS, Limbrick DD Jr, Sombati S, DeLorenzo RJ. Deshpande LS, et al. Among authors: sombati s. J Pharmacol Exp Ther. 2007 Aug;322(2):443-52. doi: 10.1124/jpet.107.123182. Epub 2007 May 4. J Pharmacol Exp Ther. 2007. PMID: 17483292

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