Marahiel MA - Search Results

1

Mechanistic and structural basis of stereospecific Cbeta-hydroxylation in calcium-dependent antibiotic, a daptomycin-type lipopeptide.

Strieker M, Kopp F, Mahlert C, Essen LO, Marahiel MA. Strieker M, et al. Among authors: marahiel ma. ACS Chem Biol. 2007 Mar 20;2(3):187-96. doi: 10.1021/cb700012y. ACS Chem Biol. 2007. PMID: 17373765

2

Stereospecific enzymatic transformation of alpha-ketoglutarate to (2S,3R)-3-methyl glutamate during acidic lipopeptide biosynthesis.

Mahlert C, Kopp F, Thirlway J, Micklefield J, Marahiel MA. Mahlert C, et al. Among authors: marahiel ma. J Am Chem Soc. 2007 Oct 3;129(39):12011-8. doi: 10.1021/ja074427i. Epub 2007 Sep 5. J Am Chem Soc. 2007. PMID: 17784761

3

The structural diversity of acidic lipopeptide antibiotics.

Strieker M, Marahiel MA. Strieker M, et al. Among authors: marahiel ma. Chembiochem. 2009 Mar 2;10(4):607-16. doi: 10.1002/cbic.200800546. Chembiochem. 2009. PMID: 19156787 Review.

4

Synthesis and derivatization of daptomycin: a chemoenzymatic route to acidic lipopeptide antibiotics.

Grünewald J, Sieber SA, Mahlert C, Linne U, Marahiel MA. Grünewald J, et al. Among authors: marahiel ma. J Am Chem Soc. 2004 Dec 29;126(51):17025-31. doi: 10.1021/ja045455t. J Am Chem Soc. 2004. PMID: 15612741

5

The thioesterase domain of the fengycin biosynthesis cluster: a structural base for the macrocyclization of a non-ribosomal lipopeptide.

Samel SA, Wagner B, Marahiel MA, Essen LO. Samel SA, et al. Among authors: marahiel ma. J Mol Biol. 2006 Jun 16;359(4):876-89. doi: 10.1016/j.jmb.2006.03.062. Epub 2006 Apr 18. J Mol Biol. 2006. PMID: 16697411

6

Chemoenzymatic design of acidic lipopeptide hybrids: new insights into the structure-activity relationship of daptomycin and A54145.

Kopp F, Grünewald J, Mahlert C, Marahiel MA. Kopp F, et al. Among authors: marahiel ma. Biochemistry. 2006 Sep 5;45(35):10474-81. doi: 10.1021/bi0609422. Biochemistry. 2006. PMID: 16939199

7

Peptide macrocyclization: the reductase of the nostocyclopeptide synthetase triggers the self-assembly of a macrocyclic imine.

Kopp F, Mahlert C, Grünewald J, Marahiel MA. Kopp F, et al. Among authors: marahiel ma. J Am Chem Soc. 2006 Dec 27;128(51):16478-9. doi: 10.1021/ja0667458. J Am Chem Soc. 2006. PMID: 17177378

8

The iterative gramicidin s thioesterase catalyzes peptide ligation and cyclization.

Hoyer KM, Mahlert C, Marahiel MA. Hoyer KM, et al. Among authors: marahiel ma. Chem Biol. 2007 Jan;14(1):13-22. doi: 10.1016/j.chembiol.2006.10.011. Chem Biol. 2007. PMID: 17254948 Free PMC article.

9

Structural and functional insights into a peptide bond-forming bidomain from a nonribosomal peptide synthetase.

Samel SA, Schoenafinger G, Knappe TA, Marahiel MA, Essen LO. Samel SA, et al. Among authors: marahiel ma. Structure. 2007 Jul;15(7):781-92. doi: 10.1016/j.str.2007.05.008. Structure. 2007. PMID: 17637339 Free article.

10

Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis.

Kopp F, Marahiel MA. Kopp F, et al. Among authors: marahiel ma. Nat Prod Rep. 2007 Aug;24(4):735-49. doi: 10.1039/b613652b. Epub 2007 May 10. Nat Prod Rep. 2007. PMID: 17653357 Review.

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