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The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype.
Vandamme N, Denecker G, Bruneel K, Blancke G, Akay Ö, Taminau J, De Coninck J, De Smedt E, Skrypek N, Van Loocke W, Wouters J, Nittner D, Köhler C, Darling DS, Cheng PF, Raaijmakers MIG, Levesque MP, Mallya UG, Rafferty M, Balint B, Gallagher WM, Brochez L, Huylebroeck D, Haigh JJ, Andries V, Rambow F, Van Vlierberghe P, Goossens S, van den Oord JJ, Marine JC, Berx G. Vandamme N, et al. Among authors: goossens s. Cancer Res. 2020 Jul 15;80(14):2983-2995. doi: 10.1158/0008-5472.CAN-19-2373. Epub 2020 Jun 5. Cancer Res. 2020. PMID: 32503808
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, Al-Saraj S, Killick R, Pickering-Brown S, Moore P, Hollingworth P, Archer N, Foy C, Walter S, Lendon C, Iwatsubo T, Morris JC, Norton J, Mann D, Janssens B, Hardy J, O'Donovan M, Jones L, Williams J, Holmans P, Owen MJ, Grupe A, Powell J, van Hengel J, Goate A, Van Roy F, Lovestone S. Busby V, et al. Among authors: goossens s. Neuromolecular Med. 2004;5(2):133-46. doi: 10.1385/NMM:5:2:133. Neuromolecular Med. 2004. PMID: 15075440
ZEB2 in T-cells and T-ALL.
De Coninck S, Berx G, Taghon T, Van Vlierberghe P, Goossens S. De Coninck S, et al. Among authors: goossens s. Adv Biol Regul. 2019 Dec;74:100639. doi: 10.1016/j.jbior.2019.100639. Epub 2019 Jul 27. Adv Biol Regul. 2019. PMID: 31383581 Review.
Zeb2 drives invasive and microbiota-dependent colon carcinoma.
Slowicka K, Petta I, Blancke G, Hoste E, Dumas E, Sze M, Vikkula H, Radaelli E, Haigh JJ, Jonckheere S, Taminau J, Vandamme N, Wullaert A, Tulchinsky E, Nittner D, Van Vlierberghe P, De Hertogh G, Baldin P, Etlioglu E, Wirapati P, Boon L, Lambrecht BN, Callewaert C, Tejpar S, Goossens S, Berx G, Vereecke L, van Loo G. Slowicka K, et al. Among authors: goossens s. Nat Cancer. 2020 Jun;1(6):620-634. doi: 10.1038/s43018-020-0070-2. Epub 2020 Jun 15. Nat Cancer. 2020. PMID: 35121975
177 results