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Page 1
Targeted deletion of Wwox reveals a tumor suppressor function.
Aqeilan RI, Trapasso F, Hussain S, Costinean S, Marshall D, Pekarsky Y, Hagan JP, Zanesi N, Kaou M, Stein GS, Lian JB, Croce CM. Aqeilan RI, et al. Among authors: trapasso f. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3949-54. doi: 10.1073/pnas.0609783104. Epub 2007 Feb 27. Proc Natl Acad Sci U S A. 2007. PMID: 17360458 Free PMC article.
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog.
Aqeilan RI, Pekarsky Y, Herrero JJ, Palamarchuk A, Letofsky J, Druck T, Trapasso F, Han SY, Melino G, Huebner K, Croce CM. Aqeilan RI, et al. Among authors: trapasso f. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4401-6. doi: 10.1073/pnas.0400805101. Proc Natl Acad Sci U S A. 2004. PMID: 15070730 Free PMC article.
Knockout mice reveal a tumor suppressor function for Testin.
Drusco A, Zanesi N, Roldo C, Trapasso F, Farber JL, Fong LY, Croce CM. Drusco A, et al. Among authors: trapasso f. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):10947-51. doi: 10.1073/pnas.0504934102. Epub 2005 Jul 20. Proc Natl Acad Sci U S A. 2005. PMID: 16033868 Free PMC article.
WWOX gene restoration prevents lung cancer growth in vitro and in vivo.
Fabbri M, Iliopoulos D, Trapasso F, Aqeilan RI, Cimmino A, Zanesi N, Yendamuri S, Han SY, Amadori D, Huebner K, Croce CM. Fabbri M, et al. Among authors: trapasso f. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15611-6. doi: 10.1073/pnas.0505485102. Epub 2005 Oct 13. Proc Natl Acad Sci U S A. 2005. PMID: 16223882 Free PMC article.
The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.
Kuroki T, Yendamuri S, Trapasso F, Matsuyama A, Aqeilan RI, Alder H, Rattan S, Cesari R, Nolli ML, Williams NN, Mori M, Kanematsu T, Croce CM. Kuroki T, et al. Among authors: trapasso f. Clin Cancer Res. 2004 Apr 1;10(7):2459-65. doi: 10.1158/1078-0432.ccr-03-0096. Clin Cancer Res. 2004. PMID: 15073125
Loss of WWOX expression in gastric carcinoma.
Aqeilan RI, Kuroki T, Pekarsky Y, Albagha O, Trapasso F, Baffa R, Huebner K, Edmonds P, Croce CM. Aqeilan RI, et al. Among authors: trapasso f. Clin Cancer Res. 2004 May 1;10(9):3053-8. doi: 10.1158/1078-0432.ccr-03-0594. Clin Cancer Res. 2004. PMID: 15131042
128 results