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Shorter survival-times following adjuvant endocrine therapy in oestrogen- and progesterone-receptor positive breast cancer overexpressing HER2 and/or with an increased expression of vascular endothelial growth factor.
Linderholm B, Bergqvist J, Hellborg H, Johansson U, Linderholm M, von Schoultz E, Elmberger G, Skoog L, Bergh J. Linderholm B, et al. Among authors: skoog l. Med Oncol. 2009 Dec;26(4):480-90. doi: 10.1007/s12032-008-9157-9. Epub 2009 Jan 7. Med Oncol. 2009. PMID: 19130322
Molecular subtype and tumor characteristics of breast cancer metastases as assessed by gene expression significantly influence patient post-relapse survival.
Tobin NP, Harrell JC, Lövrot J, Egyhazi Brage S, Frostvik Stolt M, Carlsson L, Einbeigi Z, Linderholm B, Loman N, Malmberg M, Walz T, Fernö M, Perou CM, Bergh J, Hatschek T, Lindström LS; TEX Trialists Group. Tobin NP, et al. Ann Oncol. 2015 Jan;26(1):81-88. doi: 10.1093/annonc/mdu498. Epub 2014 Oct 31. Ann Oncol. 2015. PMID: 25361981 Free PMC article. Clinical Trial.
Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts.
Pawitan Y, Bjöhle J, Amler L, Borg AL, Egyhazi S, Hall P, Han X, Holmberg L, Huang F, Klaar S, Liu ET, Miller L, Nordgren H, Ploner A, Sandelin K, Shaw PM, Smeds J, Skoog L, Wedrén S, Bergh J. Pawitan Y, et al. Among authors: skoog l. Breast Cancer Res. 2005;7(6):R953-64. doi: 10.1186/bcr1325. Epub 2005 Oct 3. Breast Cancer Res. 2005. PMID: 16280042 Free PMC article.
Gene expression profiling for prognosis using Cox regression.
Pawitan Y, Bjöhle J, Wedren S, Humphreys K, Skoog L, Huang F, Amler L, Shaw P, Hall P, Bergh J. Pawitan Y, et al. Among authors: skoog l. Stat Med. 2004 Jun 15;23(11):1767-80. doi: 10.1002/sim.1769. Stat Med. 2004. PMID: 15160407
Vascular endothelial growth factor receptor 2 and downstream p38 mitogen-activated protein kinase are possible candidate markers of intrinsic resistance to adjuvant endocrine treatment in steroid receptor positive breast cancer.
Linderholm BK, Hellborg H, Johansson U, Skoog L, Lehtiö J. Linderholm BK, et al. Among authors: skoog l. Breast Cancer Res Treat. 2011 Jan;125(2):457-65. doi: 10.1007/s10549-010-1252-x. Epub 2010 Nov 26. Breast Cancer Res Treat. 2011. PMID: 21110084 Clinical Trial.
294 results