Bruhova I - Search Results

1

Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter.

Lerche C, Bruhova I, Lerche H, Steinmeyer K, Wei AD, Strutz-Seebohm N, Lang F, Busch AE, Zhorov BS, Seebohm G. Lerche C, et al. Among authors: bruhova i. Mol Pharmacol. 2007 Jun;71(6):1503-11. doi: 10.1124/mol.106.031682. Epub 2007 Mar 8. Mol Pharmacol. 2007. PMID: 17347319

2

KvAP-based model of the pore region of shaker potassium channel is consistent with cadmium- and ligand-binding experiments.

Bruhova I, Zhorov BS. Bruhova I, et al. Biophys J. 2005 Aug;89(2):1020-9. doi: 10.1529/biophysj.105.062240. Epub 2005 May 20. Biophys J. 2005. PMID: 15908577 Free PMC article.

3

Monte Carlo-energy minimization of correolide in the Kv1.3 channel: possible role of potassium ion in ligand-receptor interactions.

Bruhova I, Zhorov BS. Bruhova I, et al. BMC Struct Biol. 2007 Jan 29;7:5. doi: 10.1186/1472-6807-7-5. BMC Struct Biol. 2007. PMID: 17261195 Free PMC article.

4

Access and binding of local anesthetics in the closed sodium channel.

Bruhova I, Tikhonov DB, Zhorov BS. Bruhova I, et al. Mol Pharmacol. 2008 Oct;74(4):1033-45. doi: 10.1124/mol.108.049759. Epub 2008 Jul 24. Mol Pharmacol. 2008. PMID: 18653802

5

Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine.

Tikhonov DB, Bruhova I, Zhorov BS. Tikhonov DB, et al. Among authors: bruhova i. FEBS Lett. 2006 Nov 13;580(26):6027-32. doi: 10.1016/j.febslet.2006.10.035. Epub 2006 Oct 24. FEBS Lett. 2006. PMID: 17070808 Free article.

6

State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels.

Tikhonov DB, Bruhova I, Garden DP, Zhorov BS. Tikhonov DB, et al. Among authors: bruhova i. Pflugers Arch. 2015 Feb;467(2):253-66. doi: 10.1007/s00424-014-1508-0. Epub 2014 Apr 15. Pflugers Arch. 2015. PMID: 24728659

7

A homology model of the pore domain of a voltage-gated calcium channel is consistent with available SCAM data.

Bruhova I, Zhorov BS. Bruhova I, et al. J Gen Physiol. 2010 Mar;135(3):261-74. doi: 10.1085/jgp.200910288. J Gen Physiol. 2010. PMID: 20176854 Free PMC article.

8

Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics.

Poulin H, Bruhova I, Timour Q, Theriault O, Beaulieu JM, Frassati D, Chahine M. Poulin H, et al. Among authors: bruhova i. Mol Pharmacol. 2014 Oct;86(4):378-89. doi: 10.1124/mol.114.093104. Epub 2014 Jul 15. Mol Pharmacol. 2014. PMID: 25028482 Free PMC article.

9

Energy for wild-type acetylcholine receptor channel gating from different choline derivatives.

Bruhova I, Gregg T, Auerbach A. Bruhova I, et al. Biophys J. 2013 Feb 5;104(3):565-74. doi: 10.1016/j.bpj.2012.11.3833. Biophys J. 2013. PMID: 23442907 Free PMC article.

10

Molecular recognition at cholinergic synapses: acetylcholine versus choline.

Bruhova I, Auerbach A. Bruhova I, et al. J Physiol. 2017 Feb 15;595(4):1253-1261. doi: 10.1113/JP273291. Epub 2016 Dec 12. J Physiol. 2017. PMID: 27779761 Free PMC article.

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