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Rap1/B-Raf signaling is activated in neuroendocrine tumors of the digestive tract and Raf kinase inhibition constitutes a putative therapeutic target.
Neuroendocrinology. 2007;85(1):45-53. doi: 10.1159/000100508. Epub 2007 Mar 5.
Neuroendocrinology. 2007.
PMID: 17341847
BRAF gene mutations are rare events in gastroenteropancreatic neuroendocrine tumors.
Tannapfel A, Vomschloss S, Karhoff D, Markwarth A, Hengge UR, Wittekind C, Arnold R, Hörsch D.
Tannapfel A, et al. Among authors: karhoff d.
Am J Clin Pathol. 2005 Feb;123(2):256-60.
Am J Clin Pathol. 2005.
PMID: 15842051
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