Bernier SG - Search Results

1

Suppression of inflammation and structural damage in experimental arthritis through molecular targeted therapy with PPI-2458.

Hannig G, Bernier SG, Hoyt JG, Doyle B, Clark E, Karp RM, Lorusso J, Westlin WF. Hannig G, et al. Among authors: bernier sg. Arthritis Rheum. 2007 Mar;56(3):850-60. doi: 10.1002/art.22402. Arthritis Rheum. 2007. PMID: 17328059 Free article.

2

An inhibitor of methionine aminopeptidase type-2, PPI-2458, ameliorates the pathophysiological disease processes of rheumatoid arthritis.

Lazarus DD, Doyle EG, Bernier SG, Rogers AB, Labenski MT, Wakefield JD, Karp RM, Clark EJ, Lorusso J, Hoyt JG, Thompson CD, Hannig G, Westlin WF. Lazarus DD, et al. Among authors: bernier sg. Inflamm Res. 2008 Jan;57(1):18-27. doi: 10.1007/s00011-007-7075-5. Inflamm Res. 2008. PMID: 18209961

3

A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis.

Bernier SG, Lazarus DD, Clark E, Doyle B, Labenski MT, Thompson CD, Westlin WF, Hannig G. Bernier SG, et al. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10768-73. doi: 10.1073/pnas.0404105101. Epub 2004 Jul 12. Proc Natl Acad Sci U S A. 2004. PMID: 15249666 Free PMC article.

4

Inhibition of melanoma tumor growth by a pharmacological inhibitor of MetAP-2, PPI-2458.

Hannig G, Lazarus DD, Bernier SG, Karp RM, Lorusso J, Qiu D, Labenski MT, Wakefield JD, Thompson CD, Westlin WF. Hannig G, et al. Among authors: bernier sg. Int J Oncol. 2006 Apr;28(4):955-63. Int J Oncol. 2006. PMID: 16525646

5

Methionine aminopeptidases type I and type II are essential to control cell proliferation.

Bernier SG, Taghizadeh N, Thompson CD, Westlin WF, Hannig G. Bernier SG, et al. J Cell Biochem. 2005 Aug 15;95(6):1191-203. doi: 10.1002/jcb.20493. J Cell Biochem. 2005. PMID: 15962312

6

Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists.

Evindar G, Bernier SG, Kavarana MJ, Doyle E, Lorusso J, Kelley MS, Halley K, Hutchings A, Wright AD, Saha AK, Hannig G, Morgan BA, Westlin WF. Evindar G, et al. Among authors: bernier sg. Bioorg Med Chem Lett. 2009 Jan 15;19(2):369-72. doi: 10.1016/j.bmcl.2008.11.072. Epub 2008 Nov 24. Bioorg Med Chem Lett. 2009. PMID: 19081720

7

Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists.

Evindar G, Satz AL, Bernier SG, Kavarana MJ, Doyle E, Lorusso J, Taghizadeh N, Halley K, Hutchings A, Kelley MS, Wright AD, Saha AK, Hannig G, Morgan BA, Westlin WF. Evindar G, et al. Among authors: bernier sg. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2315-9. doi: 10.1016/j.bmcl.2009.02.073. Epub 2009 Feb 23. Bioorg Med Chem Lett. 2009. PMID: 19282175

8

Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists.

Evindar G, Bernier SG, Doyle E, Kavarana MJ, Satz AL, Lorusso J, Blanchette HS, Saha AK, Hannig G, Morgan BA, Westlin WF. Evindar G, et al. Among authors: bernier sg. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2520-4. doi: 10.1016/j.bmcl.2010.02.098. Epub 2010 Mar 3. Bioorg Med Chem Lett. 2010. PMID: 20304639

9

Discovery of Clinical Candidate GSK1842799 As a Selective S1P1 Receptor Agonist (Prodrug) for Multiple Sclerosis.

Deng H, Bernier SG, Doyle E, Lorusso J, Morgan BA, Westlin WF, Evindar G. Deng H, et al. Among authors: bernier sg. ACS Med Chem Lett. 2013 Aug 27;4(10):942-7. doi: 10.1021/ml400194r. eCollection 2013 Oct 10. ACS Med Chem Lett. 2013. PMID: 24900589 Free PMC article.

10

Exploring amino acids derivatives as potent, selective, and direct agonists of sphingosine-1-phosphate receptor subtype-1.

Evindar G, Deng H, Bernier SG, Doyle E, Lorusso J, Morgan BA, Westlin WF. Evindar G, et al. Among authors: bernier sg. Bioorg Med Chem Lett. 2013 Jan 15;23(2):472-5. doi: 10.1016/j.bmcl.2012.11.053. Epub 2012 Nov 27. Bioorg Med Chem Lett. 2013. PMID: 23245510

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