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Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongation.
Stoll P, Bassler N, Hagemeyer CE, Eisenhardt SU, Chen YC, Schmidt R, Schwarz M, Ahrens I, Katagiri Y, Pannen B, Bode C, Peter K. Stoll P, et al. Among authors: hagemeyer ce. Arterioscler Thromb Vasc Biol. 2007 May;27(5):1206-12. doi: 10.1161/ATVBAHA.106.138875. Epub 2007 Feb 22. Arterioscler Thromb Vasc Biol. 2007. PMID: 17322097
Single-chain antibodies as new antithrombotic drugs.
Hagemeyer CE, Schwarz M, Peter K. Hagemeyer CE, et al. Semin Thromb Hemost. 2007 Mar;33(2):185-95. doi: 10.1055/s-2007-969033. Semin Thromb Hemost. 2007. PMID: 17340468 Review.
Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysis.
von zur Muhlen C, von Elverfeldt D, Moeller JA, Choudhury RP, Paul D, Hagemeyer CE, Olschewski M, Becker A, Neudorfer I, Bassler N, Schwarz M, Bode C, Peter K. von zur Muhlen C, et al. Among authors: hagemeyer ce. Circulation. 2008 Jul 15;118(3):258-67. doi: 10.1161/CIRCULATIONAHA.107.753657. Epub 2008 Jun 23. Circulation. 2008. PMID: 18574047
Dissociation of pentameric to monomeric C-reactive protein on activated platelets localizes inflammation to atherosclerotic plaques.
Eisenhardt SU, Habersberger J, Murphy A, Chen YC, Woollard KJ, Bassler N, Qian H, von Zur Muhlen C, Hagemeyer CE, Ahrens I, Chin-Dusting J, Bobik A, Peter K. Eisenhardt SU, et al. Among authors: hagemeyer ce. Circ Res. 2009 Jul 17;105(2):128-37. doi: 10.1161/CIRCRESAHA.108.190611. Epub 2009 Jun 11. Circ Res. 2009. PMID: 19520972
107 results