Ke H - Search Results

1

Crystal structures of phosphodiesterases and implications on substrate specificity and inhibitor selectivity.

Ke H, Wang H. Ke H, et al. Curr Top Med Chem. 2007;7(4):391-403. doi: 10.2174/156802607779941242. Curr Top Med Chem. 2007. PMID: 17305581 Review.

2

Mechanistic implication of crystal structures of the cyclophilin-dipeptide complexes.

Zhao Y, Ke H. Zhao Y, et al. Among authors: ke h. Biochemistry. 1996 Jun 11;35(23):7362-8. doi: 10.1021/bi960278x. Biochemistry. 1996. PMID: 8652512

3

Crystal structure of NaeI-an evolutionary bridge between DNA endonuclease and topoisomerase.

Huai Q, Colandene JD, Chen Y, Luo F, Zhao Y, Topal MD, Ke H. Huai Q, et al. Among authors: ke h. EMBO J. 2000 Jun 15;19(12):3110-8. doi: 10.1093/emboj/19.12.3110. EMBO J. 2000. PMID: 10856254 Free PMC article.

4

Crystal structures of 1-aminocyclopropane-1-carboxylate (ACC) synthase in complex with aminoethoxyvinylglycine and pyridoxal-5'-phosphate provide new insight into catalytic mechanisms.

Huai Q, Xia Y, Chen Y, Callahan B, Li N, Ke H. Huai Q, et al. Among authors: ke h. J Biol Chem. 2001 Oct 12;276(41):38210-6. doi: 10.1074/jbc.M103840200. Epub 2001 Jun 28. J Biol Chem. 2001. PMID: 11431475 Free article.

5

Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity.

Huai Q, Wang H, Sun Y, Kim HY, Liu Y, Ke H. Huai Q, et al. Among authors: ke h. Structure. 2003 Jul;11(7):865-73. doi: 10.1016/s0969-2126(03)00123-0. Structure. 2003. PMID: 12842049 Free article.

6

Crystal structure of DJ-1/RS and implication on familial Parkinson's disease.

Huai Q, Sun Y, Wang H, Chin LS, Li L, Robinson H, Ke H. Huai Q, et al. Among authors: ke h. FEBS Lett. 2003 Aug 14;549(1-3):171-5. doi: 10.1016/s0014-5793(03)00764-6. FEBS Lett. 2003. PMID: 12914946 Free article.

7

The crystal structure of AMP-bound PDE4 suggests a mechanism for phosphodiesterase catalysis.

Huai Q, Colicelli J, Ke H. Huai Q, et al. Among authors: ke h. Biochemistry. 2003 Nov 18;42(45):13220-6. doi: 10.1021/bi034653e. Biochemistry. 2003. PMID: 14609333

8

Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor 3-isobutyl-1-methylxanthine suggest a conformation determinant of inhibitor selectivity.

Huai Q, Liu Y, Francis SH, Corbin JD, Ke H. Huai Q, et al. Among authors: ke h. J Biol Chem. 2004 Mar 26;279(13):13095-101. doi: 10.1074/jbc.M311556200. Epub 2003 Dec 10. J Biol Chem. 2004. PMID: 14668322 Free article.

9

Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding.

Huai Q, Wang H, Zhang W, Colman RW, Robinson H, Ke H. Huai Q, et al. Among authors: ke h. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9624-9. doi: 10.1073/pnas.0401120101. Epub 2004 Jun 21. Proc Natl Acad Sci U S A. 2004. PMID: 15210993 Free PMC article.

10

Implications of PDE4 structure on inhibitor selectivity across PDE families.

Ke H. Ke H. Int J Impot Res. 2004 Jun;16 Suppl 1:S24-7. doi: 10.1038/sj.ijir.3901211. Int J Impot Res. 2004. PMID: 15224132 Review.

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