Leake BF - Search Results

1

Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.

Bailey DG, Dresser GK, Leake BF, Kim RB. Bailey DG, et al. Among authors: leake bf. Clin Pharmacol Ther. 2007 Apr;81(4):495-502. doi: 10.1038/sj.clpt.6100104. Epub 2007 Feb 14. Clin Pharmacol Ther. 2007. PMID: 17301733 Clinical Trial.

2

Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics.

Katz DA, Carr R, Grimm DR, Xiong H, Holley-Shanks R, Mueller T, Leake B, Wang Q, Han L, Wang PG, Edeki T, Sahelijo L, Doan T, Allen A, Spear BB, Kim RB. Katz DA, et al. Clin Pharmacol Ther. 2006 Mar;79(3):186-96. doi: 10.1016/j.clpt.2005.11.003. Epub 2006 Feb 17. Clin Pharmacol Ther. 2006. PMID: 16513443

3

Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.

Dresser GK, Bailey DG, Leake BF, Schwarz UI, Dawson PA, Freeman DJ, Kim RB. Dresser GK, et al. Among authors: leake bf. Clin Pharmacol Ther. 2002 Jan;71(1):11-20. doi: 10.1067/mcp.2002.121152. Clin Pharmacol Ther. 2002. PMID: 11823753 Clinical Trial.

4

Intestinal drug transporter expression and the impact of grapefruit juice in humans.

Glaeser H, Bailey DG, Dresser GK, Gregor JC, Schwarz UI, McGrath JS, Jolicoeur E, Lee W, Leake BF, Tirona RG, Kim RB. Glaeser H, et al. Among authors: leake bf. Clin Pharmacol Ther. 2007 Mar;81(3):362-70. doi: 10.1038/sj.clpt.6100056. Epub 2007 Jan 10. Clin Pharmacol Ther. 2007. PMID: 17215845 Clinical Trial.

5

In vitro and in vivo assessment of renal drug transporters in the disposition of mesna and dimesna.

Cutler MJ, Urquhart BL, Velenosi TJ, Meyer Zu Schwabedissen HE, Dresser GK, Leake BF, Tirona RG, Kim RB, Freeman DJ. Cutler MJ, et al. Among authors: leake bf. J Clin Pharmacol. 2012 Apr;52(4):530-42. doi: 10.1177/0091270011400414. Epub 2011 Apr 19. J Clin Pharmacol. 2012. PMID: 21505084 Clinical Trial.

6

Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation.

Tirona RG, Leake BF, Wolkoff AW, Kim RB. Tirona RG, et al. Among authors: leake bf. J Pharmacol Exp Ther. 2003 Jan;304(1):223-8. doi: 10.1124/jpet.102.043026. J Pharmacol Exp Ther. 2003. PMID: 12490595

7

Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe.

Urquhart BL, Ware JA, Tirona RG, Ho RH, Leake BF, Schwarz UI, Zaher H, Palandra J, Gregor JC, Dresser GK, Kim RB. Urquhart BL, et al. Among authors: leake bf. Pharmacogenet Genomics. 2008 May;18(5):439-48. doi: 10.1097/FPC.0b013e3282f974dc. Pharmacogenet Genomics. 2008. PMID: 18408567 Free PMC article.

8

Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity.

Schwarz UI, Meyer zu Schwabedissen HE, Tirona RG, Suzuki A, Leake BF, Mokrab Y, Mizuguchi K, Ho RH, Kim RB. Schwarz UI, et al. Among authors: leake bf. Pharmacogenet Genomics. 2011 Mar;21(3):103-14. doi: 10.1097/FPC.0b013e328342f5b1. Pharmacogenet Genomics. 2011. PMID: 21278621 Free PMC article.

9

Contribution of hepatic organic anion-transporting polypeptides to docetaxel uptake and clearance.

Lee HH, Leake BF, Teft W, Tirona RG, Kim RB, Ho RH. Lee HH, et al. Among authors: leake bf. Mol Cancer Ther. 2015 Apr;14(4):994-1003. doi: 10.1158/1535-7163.MCT-14-0547. Epub 2015 Feb 18. Mol Cancer Ther. 2015. PMID: 25695959 Free PMC article.

10

Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.

Lee HH, Leake BF, Kim RB, Ho RH. Lee HH, et al. Among authors: leake bf. Mol Pharmacol. 2017 Jan;91(1):14-24. doi: 10.1124/mol.116.105544. Epub 2016 Oct 24. Mol Pharmacol. 2017. PMID: 27777271 Free PMC article.

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