Wen JD - Search Results

1

Force unfolding kinetics of RNA using optical tweezers. I. Effects of experimental variables on measured results.

Wen JD, Manosas M, Li PT, Smith SB, Bustamante C, Ritort F, Tinoco I Jr. Wen JD, et al. Biophys J. 2007 May 1;92(9):2996-3009. doi: 10.1529/biophysj.106.094052. Epub 2007 Feb 9. Biophys J. 2007. PMID: 17293410 Free PMC article.

2

Single-molecule mechanical unfolding and folding of a pseudoknot in human telomerase RNA.

Chen G, Wen JD, Tinoco I Jr. Chen G, et al. Among authors: wen jd. RNA. 2007 Dec;13(12):2175-88. doi: 10.1261/rna.676707. Epub 2007 Oct 24. RNA. 2007. PMID: 17959928 Free PMC article.

3

Following translation by single ribosomes one codon at a time.

Wen JD, Lancaster L, Hodges C, Zeri AC, Yoshimura SH, Noller HF, Bustamante C, Tinoco I. Wen JD, et al. Nature. 2008 Apr 3;452(7187):598-603. doi: 10.1038/nature06716. Epub 2008 Mar 9. Nature. 2008. PMID: 18327250 Free PMC article.

4

Simulation and analysis of single-ribosome translation.

Tinoco I Jr, Wen JD. Tinoco I Jr, et al. Among authors: wen jd. Phys Biol. 2009 Jul 1;6(2):025006. doi: 10.1088/1478-3975/6/2/025006. Phys Biol. 2009. PMID: 19571367

5

The ribosome uses two active mechanisms to unwind messenger RNA during translation.

Qu X, Wen JD, Lancaster L, Noller HF, Bustamante C, Tinoco I Jr. Qu X, et al. Among authors: wen jd. Nature. 2011 Jul 6;475(7354):118-21. doi: 10.1038/nature10126. Nature. 2011. PMID: 21734708 Free PMC article.

6

Direct measurement of the mechanical work during translocation by the ribosome.

Liu T, Kaplan A, Alexander L, Yan S, Wen JD, Lancaster L, Wickersham CE, Fredrick K, Noller H, Tinoco I, Bustamante CJ. Liu T, et al. Among authors: wen jd. Elife. 2014 Aug 11;3:e03406. doi: 10.7554/eLife.03406. Elife. 2014. PMID: 25114092 Free PMC article.

7

Ribosome excursions during mRNA translocation mediate broad branching of frameshift pathways.

Yan S, Wen JD, Bustamante C, Tinoco I Jr. Yan S, et al. Among authors: wen jd. Cell. 2015 Feb 26;160(5):870-881. doi: 10.1016/j.cell.2015.02.003. Epub 2015 Feb 19. Cell. 2015. PMID: 25703095 Free PMC article.

8

Formation of frameshift-stimulating RNA pseudoknots is facilitated by remodeling of their folding intermediates.

Hsu CF, Chang KC, Chen YL, Hsieh PS, Lee AI, Tu JY, Chen YT, Wen JD. Hsu CF, et al. Among authors: wen jd. Nucleic Acids Res. 2021 Jul 9;49(12):6941-6957. doi: 10.1093/nar/gkab512. Nucleic Acids Res. 2021. PMID: 34161580 Free PMC article.

9

Folding a stable RNA pseudoknot through rearrangement of two hairpin structures.

Wu YJ, Wu CH, Yeh AY, Wen JD. Wu YJ, et al. Among authors: wen jd. Nucleic Acids Res. 2014 Apr;42(7):4505-15. doi: 10.1093/nar/gkt1396. Epub 2014 Jan 22. Nucleic Acids Res. 2014. PMID: 24459133 Free PMC article.

10

Coordination among tertiary base pairs results in an efficient frameshift-stimulating RNA pseudoknot.

Chen YT, Chang KC, Hu HT, Chen YL, Lin YH, Hsu CF, Chang CF, Chang KY, Wen JD. Chen YT, et al. Among authors: wen jd. Nucleic Acids Res. 2017 Jun 2;45(10):6011-6022. doi: 10.1093/nar/gkx134. Nucleic Acids Res. 2017. PMID: 28334864 Free PMC article.

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