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Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit.
Backes BJ, Longenecker K, Hamilton GL, Stewart K, Lai C, Kopecka H, von Geldern TW, Madar DJ, Pei Z, Lubben TH, Zinker BA, Tian Z, Ballaron SJ, Stashko MA, Mika AK, Beno DW, Kempf-Grote AJ, Black-Schaefer C, Sham HL, Trevillyan JM. Backes BJ, et al. Among authors: hamilton gl. Bioorg Med Chem Lett. 2007 Apr 1;17(7):2005-12. doi: 10.1016/j.bmcl.2007.01.026. Epub 2007 Jan 19. Bioorg Med Chem Lett. 2007. PMID: 17276063
Reply to: On the statistical foundation of a recent single molecule FRET benchmark.
Götz M, Barth A, Bohr SS, Börner R, Chen J, Cordes T, Erie DA, Gebhardt C, Hadzic MCAS, Hamilton GL, Hatzakis NS, Hugel T, Kisley L, Lamb DC, de Lannoy C, Mahn C, Dunukara D, de Ridder D, Sanabria H, Schimpf J, Seidel CAM, Sigel RKO, Sletfjerding MB, Thomsen J, Vollmar L, Wanninger S, Weninger KR, Xu P, Schmid S. Götz M, et al. Among authors: hamilton gl. Nat Commun. 2024 Apr 30;15(1):3626. doi: 10.1038/s41467-024-47734-2. Nat Commun. 2024. PMID: 38688911 Free PMC article. No abstract available.
Long-term ecological research in freshwaters enabled by regional biodiversity collections, stable isotope analysis, and environmental informatics.
Turner TF, Bart HL Jr, McCormick F, Besser AC, Bowes RE, Capps KA, DeArmon ES, Dillman CB, Driscoll KP, Dugger A, Hamilton GL, Harris PM, Hendrickson DA, Hoffman J, Knouft JH, Lepak RF, López-Fernández H, Montaña CG, Newsome SD, Pease AA, Smith WL, Taylor CA, Welicky RL. Turner TF, et al. Among authors: hamilton gl. Bioscience. 2023 Jul 29;73(7):479-493. doi: 10.1093/biosci/biad039. Bioscience. 2023. PMID: 37841229 Free PMC article.
DNA facilitates heterodimerization between human transcription factors FoxP1 and FoxP2 by increasing their conformational flexibility.
Coñuecar R, Asela I, Rivera M, Galaz-Davison P, González-Higueras J, Hamilton GL, Engelberger F, Ramírez-Sarmiento CA, Babul J, Sanabria H, Medina E. Coñuecar R, et al. Among authors: hamilton gl. iScience. 2023 Jun 28;26(7):107228. doi: 10.1016/j.isci.2023.107228. eCollection 2023 Jul 21. iScience. 2023. PMID: 37485372 Free PMC article.
A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories.
Götz M, Barth A, Bohr SS, Börner R, Chen J, Cordes T, Erie DA, Gebhardt C, Hadzic MCAS, Hamilton GL, Hatzakis NS, Hugel T, Kisley L, Lamb DC, de Lannoy C, Mahn C, Dunukara D, de Ridder D, Sanabria H, Schimpf J, Seidel CAM, Sigel RKO, Sletfjerding MB, Thomsen J, Vollmar L, Wanninger S, Weninger KR, Xu P, Schmid S. Götz M, et al. Among authors: hamilton gl. Nat Commun. 2022 Sep 14;13(1):5402. doi: 10.1038/s41467-022-33023-3. Nat Commun. 2022. PMID: 36104339 Free PMC article.
33 results