Lipscomb JC - Search Results

1

Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver.

Barter ZE, Bayliss MK, Beaune PH, Boobis AR, Carlile DJ, Edwards RJ, Houston JB, Lake BG, Lipscomb JC, Pelkonen OR, Tucker GT, Rostami-Hodjegan A. Barter ZE, et al. Among authors: lipscomb jc. Curr Drug Metab. 2007 Jan;8(1):33-45. doi: 10.2174/138920007779315053. Curr Drug Metab. 2007. PMID: 17266522 Review.

2

Covariation of human microsomal protein per gram of liver with age: absence of influence of operator and sample storage may justify interlaboratory data pooling.

Barter ZE, Chowdry JE, Harlow JR, Snawder JE, Lipscomb JC, Rostami-Hodjegan A. Barter ZE, et al. Among authors: lipscomb jc. Drug Metab Dispos. 2008 Dec;36(12):2405-9. doi: 10.1124/dmd.108.021311. Epub 2008 Sep 5. Drug Metab Dispos. 2008. PMID: 18775982

3

Glutathione conjugation of trichloroethylene in human liver and kidney: kinetics and individual variation.

Lash LH, Lipscomb JC, Putt DA, Parker JC. Lash LH, et al. Among authors: lipscomb jc. Drug Metab Dispos. 1999 Mar;27(3):351-9. Drug Metab Dispos. 1999. PMID: 10064565

4

In vitro to in vivo extrapolation for trichloroethylene metabolism in humans.

Lipscomb JC, Fisher JW, Confer PD, Byczkowski JZ. Lipscomb JC, et al. Toxicol Appl Pharmacol. 1998 Oct;152(2):376-87. doi: 10.1006/taap.1998.8485. Toxicol Appl Pharmacol. 1998. PMID: 9853006

5

Differences between human and rat intestinal and hepatic bisphenol A glucuronidation and the influence of alamethicin on in vitro kinetic measurements.

Mazur CS, Kenneke JF, Hess-Wilson JK, Lipscomb JC. Mazur CS, et al. Among authors: lipscomb jc. Drug Metab Dispos. 2010 Dec;38(12):2232-8. doi: 10.1124/dmd.110.034819. Epub 2010 Aug 24. Drug Metab Dispos. 2010. PMID: 20736320

6

Interindividual variance of cytochrome P450 forms in human hepatic microsomes: correlation of individual forms with xenobiotic metabolism and implications in risk assessment.

Snawder JE, Lipscomb JC. Snawder JE, et al. Among authors: lipscomb jc. Regul Toxicol Pharmacol. 2000 Oct;32(2):200-9. doi: 10.1006/rtph.2000.1424. Regul Toxicol Pharmacol. 2000. PMID: 11067776

7

Cytochrome P450-dependent metabolism of trichloroethylene: interindividual differences in humans.

Lipscomb JC, Garrett CM, Snawder JE. Lipscomb JC, et al. Toxicol Appl Pharmacol. 1997 Feb;142(2):311-8. doi: 10.1006/taap.1996.8040. Toxicol Appl Pharmacol. 1997. PMID: 9070354

8

Variance of Microsomal Protein and Cytochrome P450 2E1 and 3A Forms in Adult Human Liver.

Lipscomb JC, Teuschler LK, Swartout JC, Striley CA, Snawder JE. Lipscomb JC, et al. Toxicol Mech Methods. 2003;13(1):45-51. doi: 10.1080/15376510309821. Toxicol Mech Methods. 2003. PMID: 20021182

9

The metabolic rate constants and specific activity of human and rat hepatic cytochrome P-450 2E1 toward toluene and chloroform.

Lipscomb JC, Barton HA, Tornero-Velez R, Evans MV, Alcasey S, Snawder JE, Laskey J. Lipscomb JC, et al. J Toxicol Environ Health A. 2004 Apr 9;67(7):537-53. doi: 10.1080/15287390490425588. J Toxicol Environ Health A. 2004. PMID: 15129551

10

Application of an updated physiologically based pharmacokinetic model for chloroform to evaluate CYP2E1-mediated renal toxicity in rats and mice.

Sasso AF, Schlosser PM, Kedderis GL, Genter MB, Snawder JE, Li Z, Rieth S, Lipscomb JC. Sasso AF, et al. Among authors: lipscomb jc. Toxicol Sci. 2013 Feb;131(2):360-74. doi: 10.1093/toxsci/kfs320. Epub 2012 Nov 9. Toxicol Sci. 2013. PMID: 23143927

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