Totah RA - Search Results

1

Enantiomeric metabolic interactions and stereoselective human methadone metabolism.

Totah RA, Allen KE, Sheffels P, Whittington D, Kharasch ED. Totah RA, et al. J Pharmacol Exp Ther. 2007 Apr;321(1):389-99. doi: 10.1124/jpet.106.117580. Epub 2007 Jan 26. J Pharmacol Exp Ther. 2007. PMID: 17259447 Free article.

2

Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance.

Totah RA, Rettie AE. Totah RA, et al. Clin Pharmacol Ther. 2005 May;77(5):341-52. doi: 10.1016/j.clpt.2004.12.267. Clin Pharmacol Ther. 2005. PMID: 15900280 Review.

3

Role of CYP2B6 in stereoselective human methadone metabolism.

Totah RA, Sheffels P, Roberts T, Whittington D, Thummel K, Kharasch ED. Totah RA, et al. Anesthesiology. 2008 Mar;108(3):363-74. doi: 10.1097/ALN.0b013e3181642938. Anesthesiology. 2008. PMID: 18292673

4

Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5.

Kaspera R, Naraharisetti SB, Evangelista EA, Marciante KD, Psaty BM, Totah RA. Kaspera R, et al. Among authors: totah ra. Biochem Pharmacol. 2011 Sep 15;82(6):681-91. doi: 10.1016/j.bcp.2011.06.027. Epub 2011 Jun 24. Biochem Pharmacol. 2011. PMID: 21726541 Free PMC article.

5

Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo.

Raccor BS, Claessens AJ, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RA. Raccor BS, et al. Among authors: totah ra. Drug Metab Dispos. 2012 Jan;40(1):54-63. doi: 10.1124/dmd.111.039347. Epub 2011 Oct 5. Drug Metab Dispos. 2012. PMID: 21976622 Free PMC article.

6

A screening study of drug-drug interactions in cerivastatin users: an adverse effect of clopidogrel.

Floyd JS, Kaspera R, Marciante KD, Weiss NS, Heckbert SR, Lumley T, Wiggins KL, Tamraz B, Kwok PY, Totah RA, Psaty BM. Floyd JS, et al. Among authors: totah ra. Clin Pharmacol Ther. 2012 May;91(5):896-904. doi: 10.1038/clpt.2011.295. Epub 2012 Mar 14. Clin Pharmacol Ther. 2012. PMID: 22419147 Free PMC article.

7

Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo.

Kaspera R, Kirby BJ, Sahele T, Collier AC, Kharasch ED, Unadkat JD, Totah RA. Kaspera R, et al. Among authors: totah ra. Biochem Pharmacol. 2014 Sep 1;91(1):109-18. doi: 10.1016/j.bcp.2014.06.020. Epub 2014 Jun 25. Biochem Pharmacol. 2014. PMID: 24973543 Free PMC article.

8

A sensitive and improved throughput UPLC-MS/MS quantitation method of total cytochrome P450 mediated arachidonic acid metabolites that can separate regio-isomers and cis/trans-EETs from human plasma.

Zeigler M, Whittington D, Sotoodehnia N, Lemaitre RN, Totah RA. Zeigler M, et al. Among authors: totah ra. Chem Phys Lipids. 2018 Nov;216:162-170. doi: 10.1016/j.chemphyslip.2018.09.004. Epub 2018 Sep 7. Chem Phys Lipids. 2018. PMID: 30201384 Free PMC article.

9

The Effects of Pregnancy on Amino Acid Levels and Nitrogen Disposition.

Enthoven LF, Shi Y, Fay EE, Moreni S, Mao J, Honeyman EM, Smith CK, Whittington D, Brockerhoff SE, Isoherranen N, Totah RA, Hebert MF. Enthoven LF, et al. Among authors: totah ra. Metabolites. 2023 Feb 7;13(2):242. doi: 10.3390/metabo13020242. Metabolites. 2023. PMID: 36837861 Free PMC article.

10

Evidence of significant contribution from CYP3A5 to hepatic drug metabolism.

Huang W, Lin YS, McConn DJ 2nd, Calamia JC, Totah RA, Isoherranen N, Glodowski M, Thummel KE. Huang W, et al. Among authors: totah ra. Drug Metab Dispos. 2004 Dec;32(12):1434-45. doi: 10.1124/dmd.104.001313. Epub 2004 Sep 21. Drug Metab Dispos. 2004. PMID: 15383492

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