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Therapeutic immunisation plus cytokine and hormone therapy improves CD4 T-cell counts, restores anti-HIV-1 responses and reduces immune activation in treated chronic HIV-1 infection.
Herasimtschuk A, Downey J, Nelson M, Moyle G, Mandalia S, Sikut R, Adojaan M, Stanescu I, Gotch F, Imami N. Herasimtschuk A, et al. Vaccine. 2014 Dec 5;32(51):7005-7013. doi: 10.1016/j.vaccine.2014.09.072. Epub 2014 Oct 22. Vaccine. 2014. PMID: 25454870 Free article. Clinical Trial.
Dysregulated immunophenotypic attributes of plasmacytoid but not myeloid dendritic cells in HIV-1 infected individuals in the absence of highly active anti-retroviral therapy.
Benlahrech A, Yasmin A, Westrop SJ, Coleman A, Herasimtschuk A, Page E, Kelleher P, Gotch F, Imami N, Patterson S. Benlahrech A, et al. Among authors: herasimtschuk a. Clin Exp Immunol. 2012 Nov;170(2):212-21. doi: 10.1111/j.1365-2249.2012.04647.x. Clin Exp Immunol. 2012. PMID: 23039892 Free PMC article.
Multifarious immunotherapeutic approaches to cure HIV-1 infection.
Imami N, Herasimtschuk AA. Imami N, et al. Among authors: herasimtschuk aa. Hum Vaccin Immunother. 2015;11(9):2287-93. doi: 10.1080/21645515.2015.1021523. Hum Vaccin Immunother. 2015. PMID: 26048144 Free PMC article. Clinical Trial.
Short Communication: Therapeutic Immunization Benefits Mucosal-Associated Invariant T Cell Recovery in Contrast to Interleukin-2, Granulocyte-Macrophage Colony-Stimulating Factor, and Recombinant Human Growth Hormone Addition in HIV-1+ Treated Patients: Individual Case Reports from Phase I Trial.
Cocker ATH, Greathead L, Herasimtschuk AA, Mandalia S, Kelleher P, Imami N. Cocker ATH, et al. Among authors: herasimtschuk aa. AIDS Res Hum Retroviruses. 2019 Mar;35(3):306-309. doi: 10.1089/AID.2018.0176. Epub 2019 Feb 5. AIDS Res Hum Retroviruses. 2019. PMID: 30600702 Free article. Clinical Trial.
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial.
Parker CC, Clarke NW, Cook AD, Kynaston H, Catton CN, Cross WR, Petersen PM, Persad RA, Saad F, Bower LC, Logue J, Payne H, Forcat S, Goldstein C, Murphy C, Anderson J, Barkati M, Bottomley DM, Branagan J, Choudhury A, Chung PWM, Cogley L, Goh CL, Hoskin P, Khoo V, Malone SC, Masters L, Morris SL, Nabid A, Ong AD, Raman R, Tarver KL, Tree AC, Worlding J, Wylie JP, Zarkar AM, Parulekar WR, Parmar MKB, Sydes MR; RADICALS investigators. Parker CC, et al. Lancet. 2024 Jun 1;403(10442):2405-2415. doi: 10.1016/S0140-6736(24)00548-8. Epub 2024 May 16. Lancet. 2024. PMID: 38763154 Free PMC article. Clinical Trial.
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