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Structure-based drug design of a novel family of PPARgamma partial agonists: virtual screening, X-ray crystallography, and in vitro/in vivo biological activities.
Lu IL, Huang CF, Peng YH, Lin YT, Hsieh HP, Chen CT, Lien TW, Lee HJ, Mahindroo N, Prakash E, Yueh A, Chen HY, Goparaju CM, Chen X, Liao CC, Chao YS, Hsu JT, Wu SY. Lu IL, et al. Among authors: chen ct, chen hy, chen x. J Med Chem. 2006 May 4;49(9):2703-12. doi: 10.1021/jm051129s. J Med Chem. 2006. PMID: 16640330
One site mutation disrupts dimer formation in human DPP-IV proteins.
Chien CH, Huang LH, Chou CY, Chen YS, Han YS, Chang GG, Liang PH, Chen X. Chien CH, et al. Among authors: chen ys, chen x. J Biol Chem. 2004 Dec 10;279(50):52338-45. doi: 10.1074/jbc.M406185200. Epub 2004 Sep 24. J Biol Chem. 2004. PMID: 15448155 Free article.
β2-adrenergic receptor and astrocyte glucose metabolism.
Dong JH, Chen X, Cui M, Yu X, Pang Q, Sun JP. Dong JH, et al. Among authors: chen x. J Mol Neurosci. 2012 Oct;48(2):456-63. doi: 10.1007/s12031-012-9742-4. Epub 2012 Mar 8. J Mol Neurosci. 2012. PMID: 22399228
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