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Page 1
Solid phase synthesis and SAR of small molecule agonists for the GPR40 receptor.
McKeown SC, Corbett DF, Goetz AS, Littleton TR, Bigham E, Briscoe CP, Peat AJ, Watson SP, Hickey DM. McKeown SC, et al. Among authors: littleton tr. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1584-9. doi: 10.1016/j.bmcl.2006.12.084. Epub 2007 Jan 4. Bioorg Med Chem Lett. 2007. PMID: 17240142
Synthesis and activity of small molecule GPR40 agonists.
Garrido DM, Corbett DF, Dwornik KA, Goetz AS, Littleton TR, McKeown SC, Mills WY, Smalley TL Jr, Briscoe CP, Peat AJ. Garrido DM, et al. Among authors: littleton tr. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1840-5. doi: 10.1016/j.bmcl.2006.01.007. Epub 2006 Jan 24. Bioorg Med Chem Lett. 2006. PMID: 16439116
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.
Briscoe CP, Peat AJ, McKeown SC, Corbett DF, Goetz AS, Littleton TR, McCoy DC, Kenakin TP, Andrews JL, Ammala C, Fornwald JA, Ignar DM, Jenkinson S. Briscoe CP, et al. Among authors: littleton tr. Br J Pharmacol. 2006 Jul;148(5):619-28. doi: 10.1038/sj.bjp.0706770. Epub 2006 May 15. Br J Pharmacol. 2006. PMID: 16702987 Free PMC article.