Alexander PA - Search Results

1

Hydrogen-deuterium exchange in free and prodomain-complexed subtilisin.

Sari N, Ruan B, Fisher KE, Alexander PA, Orban J, Bryan PN. Sari N, et al. Among authors: alexander pa. Biochemistry. 2007 Jan 23;46(3):652-8. doi: 10.1021/bi061601r. Biochemistry. 2007. PMID: 17223687

2

Engineering subtilisin into a fluoride-triggered processing protease useful for one-step protein purification.

Ruan B, Fisher KE, Alexander PA, Doroshko V, Bryan PN. Ruan B, et al. Among authors: alexander pa. Biochemistry. 2004 Nov 23;43(46):14539-46. doi: 10.1021/bi048177j. Biochemistry. 2004. PMID: 15544324

3

Directed coevolution of stability and catalytic activity in calcium-free subtilisin.

Strausberg SL, Ruan B, Fisher KE, Alexander PA, Bryan PN. Strausberg SL, et al. Among authors: alexander pa. Biochemistry. 2005 Mar 8;44(9):3272-9. doi: 10.1021/bi047806m. Biochemistry. 2005. PMID: 15736937

4

Directed evolution of highly homologous proteins with different folds by phage display: implications for the protein folding code.

Alexander PA, Rozak DA, Orban J, Bryan PN. Alexander PA, et al. Biochemistry. 2005 Nov 1;44(43):14045-54. doi: 10.1021/bi051231r. Biochemistry. 2005. PMID: 16245920

5

Using offset recombinant polymerase chain reaction to identify functional determinants in a common family of bacterial albumin binding domains.

Rozak DA, Alexander PA, He Y, Chen Y, Orban J, Bryan PN. Rozak DA, et al. Among authors: alexander pa. Biochemistry. 2006 Mar 14;45(10):3263-71. doi: 10.1021/bi051926s. Biochemistry. 2006. PMID: 16519521

6

Mechanism of the kinetically-controlled folding reaction of subtilisin.

Fisher KE, Ruan B, Alexander PA, Wang L, Bryan PN. Fisher KE, et al. Among authors: alexander pa. Biochemistry. 2007 Jan 23;46(3):640-51. doi: 10.1021/bi061600z. Biochemistry. 2007. PMID: 17223686

7

The design and characterization of two proteins with 88% sequence identity but different structure and function.

Alexander PA, He Y, Chen Y, Orban J, Bryan PN. Alexander PA, et al. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):11963-8. doi: 10.1073/pnas.0700922104. Epub 2007 Jul 3. Proc Natl Acad Sci U S A. 2007. PMID: 17609385 Free PMC article.

8

Solution NMR structures of IgG binding domains with artificially evolved high levels of sequence identity but different folds.

He Y, Yeh DC, Alexander P, Bryan PN, Orban J. He Y, et al. Biochemistry. 2005 Nov 1;44(43):14055-61. doi: 10.1021/bi051232j. Biochemistry. 2005. PMID: 16245921

9

NMR structures of two designed proteins with high sequence identity but different fold and function.

He Y, Chen Y, Alexander P, Bryan PN, Orban J. He Y, et al. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14412-7. doi: 10.1073/pnas.0805857105. Epub 2008 Sep 16. Proc Natl Acad Sci U S A. 2008. PMID: 18796611 Free PMC article.

10

Cation-dependent stability of subtilisin.

Alexander PA, Ruan B, Bryan PN. Alexander PA, et al. Biochemistry. 2001 Sep 4;40(35):10634-9. doi: 10.1021/bi010797m. Biochemistry. 2001. PMID: 11524007

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