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An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes.
Filippova GN, Fagerlie S, Klenova EM, Myers C, Dehner Y, Goodwin G, Neiman PE, Collins SJ, Lobanenkov VV. Filippova GN, et al. Among authors: lobanenkov vv. Mol Cell Biol. 1996 Jun;16(6):2802-13. doi: 10.1128/MCB.16.6.2802. Mol Cell Biol. 1996. PMID: 8649389 Free PMC article.
Molecular weight abnormalities of the CTCF transcription factor: CTCF migrates aberrantly in SDS-PAGE and the size of the expressed protein is affected by the UTRs and sequences within the coding region of the CTCF gene.
Klenova EM, Nicolas RH, U S, Carne AF, Lee RE, Lobanenkov VV, Goodwin GH. Klenova EM, et al. Among authors: lobanenkov vv. Nucleic Acids Res. 1997 Feb 1;25(3):466-74. doi: 10.1093/nar/25.3.466. Nucleic Acids Res. 1997. PMID: 9016583 Free PMC article.
A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers.
Filippova GN, Lindblom A, Meincke LJ, Klenova EM, Neiman PE, Collins SJ, Doggett NA, Lobanenkov VV. Filippova GN, et al. Among authors: lobanenkov vv. Genes Chromosomes Cancer. 1998 May;22(1):26-36. Genes Chromosomes Cancer. 1998. PMID: 9591631
117 results