Leung TN - Search Results

1

Plasma placental RNA allelic ratio permits noninvasive prenatal chromosomal aneuploidy detection.

Lo YM, Tsui NB, Chiu RW, Lau TK, Leung TN, Heung MM, Gerovassili A, Jin Y, Nicolaides KH, Cantor CR, Ding C. Lo YM, et al. Among authors: leung tn. Nat Med. 2007 Feb;13(2):218-23. doi: 10.1038/nm1530. Epub 2007 Jan 7. Nat Med. 2007. PMID: 17206148

2

Prenatal exclusion of beta thalassaemia major by examination of maternal plasma.

Chiu RW, Lau TK, Leung TN, Chow KC, Chui DH, Lo YM. Chiu RW, et al. Among authors: leung tn. Lancet. 2002 Sep 28;360(9338):998-1000. doi: 10.1016/s0140-6736(02)11086-5. Lancet. 2002. PMID: 12383672

3

mRNA of placental origin is readily detectable in maternal plasma.

Ng EK, Tsui NB, Lau TK, Leung TN, Chiu RW, Panesar NS, Lit LC, Chan KW, Lo YM. Ng EK, et al. Among authors: leung tn. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4748-53. doi: 10.1073/pnas.0637450100. Epub 2003 Mar 18. Proc Natl Acad Sci U S A. 2003. PMID: 12644709 Free PMC article.

4

Circulating placental RNA in maternal plasma is associated with a preponderance of 5' mRNA fragments: implications for noninvasive prenatal diagnosis and monitoring.

Wong BC, Chiu RW, Tsui NB, Chan KC, Chan LW, Lau TK, Leung TN, Lo YM. Wong BC, et al. Among authors: leung tn. Clin Chem. 2005 Oct;51(10):1786-95. doi: 10.1373/clinchem.2005.052340. Epub 2005 Aug 4. Clin Chem. 2005. PMID: 16081506

5

Detection of the placental epigenetic signature of the maspin gene in maternal plasma.

Chim SS, Tong YK, Chiu RW, Lau TK, Leung TN, Chan LY, Oudejans CB, Ding C, Lo YM. Chim SS, et al. Among authors: leung tn. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14753-8. doi: 10.1073/pnas.0503335102. Epub 2005 Oct 3. Proc Natl Acad Sci U S A. 2005. PMID: 16203989 Free PMC article.

6

Noninvasive prenatal detection of fetal trisomy 18 by epigenetic allelic ratio analysis in maternal plasma: Theoretical and empirical considerations.

Tong YK, Ding C, Chiu RW, Gerovassili A, Chim SS, Leung TY, Leung TN, Lau TK, Nicolaides KH, Lo YM. Tong YK, et al. Among authors: leung ty, leung tn. Clin Chem. 2006 Dec;52(12):2194-202. doi: 10.1373/clinchem.2006.076851. Epub 2006 Oct 13. Clin Chem. 2006. PMID: 17040955

7

Hypermethylated RASSF1A in maternal plasma: A universal fetal DNA marker that improves the reliability of noninvasive prenatal diagnosis.

Chan KC, Ding C, Gerovassili A, Yeung SW, Chiu RW, Leung TN, Lau TK, Chim SS, Chung GT, Nicolaides KH, Lo YM. Chan KC, et al. Among authors: leung tn. Clin Chem. 2006 Dec;52(12):2211-8. doi: 10.1373/clinchem.2006.074997. Epub 2006 Oct 26. Clin Chem. 2006. PMID: 17068167

8

Detection of restriction enzyme-digested target DNA by PCR amplification using a stem-loop primer: application to the detection of hypomethylated fetal DNA in maternal plasma.

Tong YK, Chiu RW, Leung TY, Ding C, Lau TK, Leung TN, Lo YM. Tong YK, et al. Among authors: leung ty, leung tn. Clin Chem. 2007 Nov;53(11):1906-14. doi: 10.1373/clinchem.2007.092619. Epub 2007 Sep 27. Clin Chem. 2007. PMID: 17901110

9

Circulating fetal RNA in maternal plasma.

Poon LL, Leung TN, Lau TK, Lo YM. Poon LL, et al. Among authors: leung tn. Ann N Y Acad Sci. 2001 Sep;945:207-10. doi: 10.1111/j.1749-6632.2001.tb03887.x. Ann N Y Acad Sci. 2001. PMID: 11708480

10

Genetic screening and diagnosis.

Lau TK, Leung TN. Lau TK, et al. Among authors: leung tn. Curr Opin Obstet Gynecol. 2005 Apr;17(2):163-9. doi: 10.1097/01.gco.0000162187.99219.e0. Curr Opin Obstet Gynecol. 2005. PMID: 15758610 Review.

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