Kunkel MT - Search Results

1

Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter.

Kunkel MT, Toker A, Tsien RY, Newton AC. Kunkel MT, et al. J Biol Chem. 2007 Mar 2;282(9):6733-42. doi: 10.1074/jbc.M608086200. Epub 2006 Dec 21. J Biol Chem. 2007. PMID: 17189263 Free PMC article.

2

Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter.

Kunkel MT, Ni Q, Tsien RY, Zhang J, Newton AC. Kunkel MT, et al. J Biol Chem. 2005 Feb 18;280(7):5581-7. doi: 10.1074/jbc.M411534200. Epub 2004 Dec 6. J Biol Chem. 2005. PMID: 15583002 Free PMC article.

3

Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling.

Gallegos LL, Kunkel MT, Newton AC. Gallegos LL, et al. Among authors: kunkel mt. J Biol Chem. 2006 Oct 13;281(41):30947-56. doi: 10.1074/jbc.M603741200. Epub 2006 Aug 10. J Biol Chem. 2006. PMID: 16901905 Free article.

4

The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity.

Kunkel MT, Garcia EL, Kajimoto T, Hall RA, Newton AC. Kunkel MT, et al. J Biol Chem. 2009 Sep 4;284(36):24653-61. doi: 10.1074/jbc.M109.024547. Epub 2009 Jul 6. J Biol Chem. 2009. PMID: 19581308 Free PMC article.

5

Calcium transduces plasma membrane receptor signals to produce diacylglycerol at Golgi membranes.

Kunkel MT, Newton AC. Kunkel MT, et al. J Biol Chem. 2010 Jul 23;285(30):22748-52. doi: 10.1074/jbc.C110.123133. Epub 2010 Jun 2. J Biol Chem. 2010. PMID: 20519514 Free PMC article.

6

Active site inhibitors protect protein kinase C from dephosphorylation and stabilize its mature form.

Gould CM, Antal CE, Reyes G, Kunkel MT, Adams RA, Ziyar A, Riveros T, Newton AC. Gould CM, et al. Among authors: kunkel mt. J Biol Chem. 2011 Aug 19;286(33):28922-28930. doi: 10.1074/jbc.M111.272526. Epub 2011 Jun 29. J Biol Chem. 2011. PMID: 21715334 Free PMC article.

7

Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin.

Bossuyt J, Chang CW, Helmstadter K, Kunkel MT, Newton AC, Campbell KS, Martin JL, Bossuyt S, Robia SL, Bers DM. Bossuyt J, et al. Among authors: kunkel mt. J Biol Chem. 2011 Sep 23;286(38):33390-400. doi: 10.1074/jbc.M111.246447. Epub 2011 Jul 27. J Biol Chem. 2011. PMID: 21795686 Free PMC article.

8

Imaging kinase activity at protein scaffolds.

Kunkel MT, Newton AC. Kunkel MT, et al. Methods Mol Biol. 2014;1071:129-37. doi: 10.1007/978-1-62703-622-1_10. Methods Mol Biol. 2014. PMID: 24052385 Free PMC article.

9

Intramolecular conformational changes optimize protein kinase C signaling.

Antal CE, Violin JD, Kunkel MT, Skovsø S, Newton AC. Antal CE, et al. Among authors: kunkel mt. Chem Biol. 2014 Apr 24;21(4):459-469. doi: 10.1016/j.chembiol.2014.02.008. Epub 2014 Mar 13. Chem Biol. 2014. PMID: 24631122 Free PMC article.

10

Protein kinase d inhibitors uncouple phosphorylation from activity by promoting agonist-dependent activation loop phosphorylation.

Kunkel MT, Newton AC. Kunkel MT, et al. Chem Biol. 2015 Jan 22;22(1):98-106. doi: 10.1016/j.chembiol.2014.11.014. Epub 2014 Dec 31. Chem Biol. 2015. PMID: 25556943 Free PMC article.

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