Derijks LJ - Search Results

1

Toxicity of 6-thioguanine: no hepatotoxicity in a series of IBD patients treated with long-term, low dose 6-thioguanine. Some evidence for dose or metabolite level dependent effects?

Gilissen LP, Derijks LJ, Driessen A, Bos LP, Hooymans PM, Stockbrügger RW, Engels LG. Gilissen LP, et al. Among authors: derijks lj. Dig Liver Dis. 2007 Feb;39(2):156-9. doi: 10.1016/j.dld.2006.10.007. Epub 2006 Dec 26. Dig Liver Dis. 2007. PMID: 17188950

2

The pharmacokinetic effect of discontinuation of mesalazine on mercaptopurine metabolite levels in inflammatory bowel disease patients.

Gilissen LP, Bierau J, Derijks LJ, Bos LP, Hooymans PM, van Gennip A, Stockbrügger RW, Engels LG. Gilissen LP, et al. Among authors: derijks lj. Aliment Pharmacol Ther. 2005 Oct 1;22(7):605-11. doi: 10.1111/j.1365-2036.2005.02630.x. Aliment Pharmacol Ther. 2005. PMID: 16181300 Clinical Trial.

3

Pancytopenia due to high 6-methylmercaptopurine levels in a 6-mercaptopurine treated patient with Crohn's disease.

Gilissen LP, Derijks LJ, Verhoeven HM, Bierau J, Hooymans PM, Hommes DW, Engels LG. Gilissen LP, et al. Among authors: derijks lj. Dig Liver Dis. 2007 Feb;39(2):182-6. doi: 10.1016/j.dld.2006.05.026. Epub 2006 Aug 1. Dig Liver Dis. 2007. PMID: 16880012

4

Absence of nodular regenerative hyperplasia after low-dose 6-thioguanine maintenance therapy in inflammatory bowel disease patients.

de Boer NK, Zondervan PE, Gilissen LP, den Hartog G, Westerveld BD, Derijks LJ, Bloemena E, Engels LG, van Bodegraven AA, Mulder CJ. de Boer NK, et al. Among authors: derijks lj. Dig Liver Dis. 2008 Feb;40(2):108-13. doi: 10.1016/j.dld.2007.10.013. Epub 2007 Dec 20. Dig Liver Dis. 2008. PMID: 18083079 Clinical Trial.

5

Safety of thiopurines in the treatment of inflammatory bowel disease.

de Jong DJ, Derijks LJ, Naber AH, Hooymans PM, Mulder CJ. de Jong DJ, et al. Among authors: derijks lj. Scand J Gastroenterol Suppl. 2003;(239):69-72. doi: 10.1080/00855920310002726. Scand J Gastroenterol Suppl. 2003. PMID: 14743886 Review.

6

Review article: thiopurines in inflammatory bowel disease.

Derijks LJ, Gilissen LP, Hooymans PM, Hommes DW. Derijks LJ, et al. Aliment Pharmacol Ther. 2006 Sep 1;24(5):715-29. doi: 10.1111/j.1365-2036.2006.02980.x. Aliment Pharmacol Ther. 2006. PMID: 16918876 Review.

7

Extended thiopurine metabolite assessment during 6-thioguanine therapy for immunomodulation in Crohn's disease.

de Boer NK, Derijks LJ, Keizer-Garritsen JJ, Lambooy LH, Ruitenbeek W, Hooymans PM, van Bodegraven AA, de Jong DJ. de Boer NK, et al. Among authors: derijks lj. J Clin Pharmacol. 2007 Feb;47(2):187-91. doi: 10.1177/0091270006294403. J Clin Pharmacol. 2007. PMID: 17244769 Clinical Trial.

8

Therapeutic drug monitoring in patients with inflammatory bowel disease and established azathioprine therapy.

Gilissen LP, Derijks LJ, Bos LP, Bus PJ, Hooymans PM, Engels LG. Gilissen LP, et al. Among authors: derijks lj. Clin Drug Investig. 2004;24(8):479-86. doi: 10.2165/00044011-200424080-00006. Clin Drug Investig. 2004. PMID: 17523708

9

Early prediction of thiopurine-induced hepatotoxicity in inflammatory bowel disease.

Wong DR, Coenen MJ, Derijks LJ, Vermeulen SH, van Marrewijk CJ, Klungel OH, Scheffer H, Franke B, Guchelaar HJ, de Jong DJ, Engels LG, Verbeek AL, Hooymans PM; TOPIC Recruitment Team. Wong DR, et al. Among authors: derijks lj. Aliment Pharmacol Ther. 2017 Feb;45(3):391-402. doi: 10.1111/apt.13879. Epub 2016 Dec 12. Aliment Pharmacol Ther. 2017. PMID: 27943397 Clinical Trial.

10

The glutathione transferase Mu null genotype leads to lower 6-MMPR levels in patients treated with azathioprine but not with mercaptopurine.

Broekman MMTJ, Wong DR, Wanten GJA, Roelofs HM, van Marrewijk CJ, Klungel OH, Verbeek ALM, Hooymans PM, Guchelaar HJ, Scheffer H, Derijks LJJ, Coenen MJH, de Jong DJ. Broekman MMTJ, et al. Pharmacogenomics J. 2018 Jan;18(1):160-166. doi: 10.1038/tpj.2016.87. Epub 2017 Jan 3. Pharmacogenomics J. 2018. PMID: 28045129

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