Kinetic mechanism of DNA polymerase I (Klenow).
Kuchta RD, Mizrahi V, Benkovic PA, Johnson KA, Benkovic SJ.
Kuchta RD, et al. Among authors: mizrahi v.
Biochemistry. 1987 Dec 15;26(25):8410-7. doi: 10.1021/bi00399a057.
Biochemistry. 1987.
PMID: 3327522
The rate is not limited by the actual polymerization but by a separate step, possibly important in ensuring fidelity [Mizrahi, V., Henrie, R. N., Marlier, J. F., Johnson, K. A., & Benkovic, S. J. (1985) Biochemistry 24, 4010-4018]. ...
The rate is not limited by the actual polymerization but by a separate step, possibly important in ensuring fidelity [Mizrahi, V …